Pathophysiology of atherosclerosis

S Jebari-Benslaiman, U Galicia-García… - International journal of …, 2022 - mdpi.com
Atherosclerosis is the main risk factor for cardiovascular disease (CVD), which is the leading
cause of mortality worldwide. Atherosclerosis is initiated by endothelium activation and …

Epigenetic regulation in cardiovascular disease: mechanisms and advances in clinical trials

Y Shi, H Zhang, S Huang, L Yin, F Wang… - … and Targeted Therapy, 2022 - nature.com
Epigenetics is closely related to cardiovascular diseases. Genome-wide linkage and
association analyses and candidate gene approaches illustrate the multigenic complexity of …

Non-coding RNAs in human health and disease: potential function as biomarkers and therapeutic targets

T Loganathan, GP Doss C - Functional & integrative genomics, 2023 - Springer
Human diseases have been a critical threat from the beginning of human history. Knowing
the origin, course of action and treatment of any disease state is essential. A microscopic …

[HTML][HTML] Exosomes in atherosclerosis: performers, bystanders, biomarkers, and therapeutic targets

C Wang, Z Li, Y Liu, L Yuan - Theranostics, 2021 - ncbi.nlm.nih.gov
Exosomes are nanosized lipid vesicles originating from the endosomal system that carry
many macromolecules from their parental cells and play important roles in intercellular …

[图书][B] RNA, the epicenter of genetic information

J Mattick, P Amaral - 2023 - library.oapen.org
The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

[HTML][HTML] Focus: the science of stress: oxidative stress and inflammation in cardiovascular diseases and cancer: role of non-coding RNAs

P Ginckels, P Holvoet - The Yale Journal of Biology and Medicine, 2022 - ncbi.nlm.nih.gov
Abstract High oxidative stress, Th1/Th17 immune response, M1 macrophage inflammation,
and cell death are associated with cardiovascular diseases. Controlled oxidative stress …

Signaling by LncRNAs: Structure, cellular homeostasis, and disease pathology

R Nadhan, C Isidoro, YS Song, DN Dhanasekaran - Cells, 2022 - mdpi.com
The cellular signaling network involves co-ordinated regulation of numerous signaling
molecules that aid the maintenance of cellular as well as organismal homeostasis. Aberrant …

The impact of mechanical cues on the metabolomic and transcriptomic profiles of human dermal fibroblasts cultured in Ultrashort Self-assembling peptide 3D scaffolds

S Abdelrahman, R Ge, HH Susapto, Y Liu, F Samkari… - ACS …, 2023 - ACS Publications
Cells' interactions with their microenvironment influence their morphological features and
regulate crucial cellular functions including proliferation, differentiation, metabolism, and …

Long noncoding RNAs in atherosclerosis and vascular injury: pathobiology, biomarkers, and targets for therapy

JB Pierce, MW Feinberg - Arteriosclerosis, thrombosis, and …, 2020 - Am Heart Assoc
Despite major advances in the primary and secondary prevention of atherosclerosis and its
risk factors, atherosclerotic cardiovascular disease remains a major clinical and financial …

[HTML][HTML] The regulation of circRNA and lncRNAprotein binding in cardiovascular diseases: Emerging therapeutic targets

H Zhao, Z Tan, J Zhou, Y Wu, Q Hu, Q Ling… - Biomedicine & …, 2023 - Elsevier
Noncoding ribonucleic acids (ncRNAs) are a class of ribonucleic acids (RNAs) that carry
cellular information and perform essential functions. This class encompasses various RNAs …