New concepts concerning the neural mechanisms of amblyopia and their clinical implications

AMF Wong - Canadian Journal of Ophthalmology, 2012 - Elsevier
Amblyopia is a visual impairment secondary to abnormal visual experience (eg, strabismus,
anisometropia, form deprivation) during early childhood that cannot be corrected …

Using magnetic resonance imaging to assess visual deficits: a review

HDH Brown, RL Woodall, RE Kitching… - Ophthalmic and …, 2016 - Wiley Online Library
Purpose Over the last two decades, magnetic resonance imaging (MRI) has been widely
used in neuroscience research to assess both structure and function in the brain in health …

Neuroimaging of amblyopia and binocular vision: a review

O Joly, E Frankó - Frontiers in integrative neuroscience, 2014 - frontiersin.org
Amblyopia is a cerebral visual impairment considered to derive from abnormal visual
experience (eg, strabismus, anisometropia). Amblyopia, first considered as a monocular …

[HTML][HTML] The structural properties of major white matter tracts in strabismic amblyopia

Y Duan, AM Norcia, JD Yeatman… - … ophthalmology & visual …, 2015 - arvojournals.org
Purpose: In order to better understand whether white matter structural deficits are present in
strabismic amblyopia, we performed a survey of the tissue properties of 28 major white …

Is the cortical deficit in amblyopia due to reduced cortical magnification, loss of neural resolution, or neural disorganization?

S Clavagnier, SO Dumoulin, RF Hess - Journal of Neuroscience, 2015 - Soc Neuroscience
The neural basis of amblyopia is a matter of debate. The following possibilities have been
suggested: loss of foveal cells, reduced cortical magnification, loss of spatial resolution of …

[HTML][HTML] The relationship between anisometropia, patient age, and the development of amblyopia

SP Donahue - Transactions of the American Ophthalmological …, 2005 - ncbi.nlm.nih.gov
Purpose Anisometropia is a common cause of amblyopia. The relationship between
anisometropia, patient age, and the development of amblyopia is unknown. Photoscreening …

Neuroanatomy of adult strabismus: a voxel-based morphometric analysis of magnetic resonance structural scans

S Chan, K Tang, K Lam, L Chan, JD Mendola… - Neuroimage, 2004 - Elsevier
Cerebral deficit has been implicated in the genesis of strabismus and in the mechanisms
adopted to compensate for the visual disorder. Voxel-based morphometry (VBM) was …

[HTML][HTML] Cortical deficits in human amblyopia: their regional distribution and their relationship to the contrast detection deficit

X Li, SO Dumoulin, B Mansouri… - … ophthalmology & visual …, 2007 - arvojournals.org
purpose. The understanding of the site and nature of the cortical processing deficit in human
amblyopia awaits the resolution of three fundamental questions about which there is, at …

Decreased activation of the lateral geniculate nucleus in a patient with anisometropic amblyopia demonstrated by functional magnetic resonance imaging

A Miki, GT Liu, ZG Goldsmith, CSJ Liu… - Ophthalmologica, 2003 - karger.com
Although postmortem morphological changes in the lateral geniculate nucleus (LGN) have
been reported in human amblyopia, LGN function during monocular viewing by amblyopic …

Monocular activation of V1 and V2 in amblyopic adults measured with functional magnetic resonance imaging

IP Conner, JV Odom, TL Schwartz… - Journal of American …, 2007 - Elsevier
PURPOSE: Although previous neuroimaging efforts clearly indicate visual cortical
dysfunction in adults with amblyopia, the extent of abnormalities remains unclear …