Indication and management of allogeneic haematopoietic stem-cell transplantation in myelofibrosis: updated recommendations by the EBMT/ELN International …

N Kröger, A Bacigalupo, T Barbui… - The Lancet …, 2024 - thelancet.com
New options for medical therapy and risk scoring systems containing molecular data are
leading to increased complexity in the management of patients with myelofibrosis. To inform …

Myeloproliferative neoplasms, version 3.2022, NCCN clinical practice guidelines in oncology

AT Gerds, J Gotlib, H Ali, P Bose, A Dunbar… - Journal of the National …, 2022 - jnccn.org
The classic Philadelphia chromosome–negative myeloproliferative neoplasms (MPN)
consist of myelofibrosis, polycythemia vera, and essential thrombocythemia and are a …

The development of post-transplant cyclophosphamide: Half a century of translational team science

PV O'Donnell, RJ Jones - Blood reviews, 2023 - Elsevier
Close HLA matching of donors and recipients has been the dogma for successful allogeneic
blood or marrow transplantation (alloBMT), to limit the complications of graft-versus-host …

[HTML][HTML] Haploidentical donor hematopoietic cell transplantation for myelodysplastic/myeloproliferative overlap neoplasms: results from a North American collaboration

T Jain, HL Tsai, H Elmariah, P Vachhani… - …, 2023 - ncbi.nlm.nih.gov
Haploidentical donors offer a potentially readily available donor, especially for non-White
patients, for hematopoietic cell transplantation (HCT). In this North American collaboration …

Donor types and outcomes of transplantation in myelofibrosis: a CIBMTR study

T Jain, N Estrada-Merly, MQ Salas, S Kim… - Blood …, 2024 - ashpublications.org
We evaluate the impact of donor types on outcomes of hematopoietic cell transplantation
(HCT) in myelofibrosis, using the Center for International Blood and Marrow Transplant …

[HTML][HTML] Outcome heterogeneity of TP53-mutated myeloid neoplasms and the role of allogeneic hematopoietic cell transplantation

S Pasca, SD Haldar, A Ambinder, JA Webster… - …, 2024 - ncbi.nlm.nih.gov
TP53 mutations are present in up to 20% of patients with de novo myeloid neoplasms (MN)
and nearly 40% with myeloid neoplasm post cytotoxic therapy (MN-pCT). They are …

A simple prognostic system in patients with myelofibrosis undergoing allogeneic stem cell transplantation: a CIBMTR/EBMT analysis

R Tamari, DP McLornan, KW Ahn… - Blood …, 2023 - ashpublications.org
To develop a prognostic model for patients undergoing allogeneic hematopoietic cell
transplantation (allo-HCT) for myelofibrosis (MF), we examined the data of 623 patients …

Graft Failure Incidence, Risk Factors, and Outcomes in Patients Undergoing Non-Myeloablative Allogeneic Hematopoietic Cell Transplantation Using Post-Transplant …

JR Mata, M Zahurak, N Rosen, AE DeZern… - … and Cellular Therapy, 2024 - Elsevier
Graft failure (GF) is a major complication of allogeneic hematopoietic cell transplantation
(alloHCT) that results in significant morbidity and mortality. Post-transplant …

The next horizon now that everyone has a donor: Precision allogeneic transplantation

RJ Jones, A Bacigalupo - Blood Reviews, 2023 - Elsevier
Post-transplant cyclophosphamide (PTCy) allows safe and effective partially matched donor
allogeneic blood or marrow transplantation (alloBMT), so that almost everyone in need of …

[HTML][HTML] Successful outcome in patients with myelofibrosis undergoing allogeneic donor hematopoietic cell transplantation using reduced doses of post …

I García-Cadenas, S Redondo, A Esquirol… - … and cellular therapy, 2023 - Elsevier
Engraftment and nonrelapse mortality (NRM) after allogeneic hematopoietic cell
transplantation (allo-HCT) depend greatly on the transplantation platform in patients with …