Clostridioides difficile bacteria can cause life-threatening diarrhea and colitis owing to
limited treatment options and unacceptably high recurrence rates among infected patients …

Clostridioides difficile is the leading cause of healthcare-associated infection in the US and
considered an urgent threat by the Centers for Disease Control and Prevention (CDC). Only …

Clostridioides difficile is an enteric pathogen that can cause a range of illnesses from mild
diarrhea to pseudomembranous colitis and even death. This pathogen often takes …

Clostridioides difficile (C. difficile) is a gram-positive, anaerobic spore-forming bacterium and
a major cause of antibiotic-associated diarrhea. Humans are naturally resistant to C. difficile …

Clostridioides difficile, the causative agent of antibiotic-associated diarrhea and
pseudomembranous colitis, has emerged as a major enteric pathogen in recent years …

Clostridioides difficile infection is a global health threat and remains the primary cause of
hospital-acquired infections worldwide. The burgeoning incidence and severity of infections …

Cis-prenyltransferases such as undecaprenyl diphosphate synthase (UPPS) and
decaprenyl diphosphate synthase (DPPS) are essential enzymes in bacteria and are …

Incidence of Clostridioides difficile infection (CDI) has been increasing in recent decades
due to different factors, namely (i) extended use of broad-spectrum antibiotics,(ii) …

Clostridioides difficile is a major cause of nosocomial infections, often associated with
individuals who have gut dysbiosis from previous antibiotic therapies. C. difficile infections …

Small molecules that can reduce the neurotoxic beta-amyloid (Aβ) aggregates in the brain
provide a potential treatment for Alzheimer disease (AD). Most screening methods for small …