The real-time, dynamic optical visualization of lesions and margins ensures not only
complete resection of the malignant tissues but also better preservation of the vital …

Fluorescence-guided surgery is an intraoperative optical imaging method that provides
surgeons with real-time guidance for the delineation of tumours. Currently, in phase 1 and 2 …

Optical imaging has become an indispensable technology in the clinic. The molecular
design of cell-targeted and highly sensitive materials, the validation of specific disease …

The rapid development of fluorescence imaging for intraoperative navigation has spurred
further development of targeted fluorescent probes in the past decade. Only a few …

Microscopic evaluation of resected tissue plays a central role in the surgical management of
cancer. Because optical microscopes have a limited depth-of-field (DOF), resected tissue is …

Fluorescence imaging is an emerging technology that can provide real-time information
about the operating field during cancer surgery. Non-specific fluorescent agents, used for …

Abstract γ-Glutamyltranspeptidase (GGT) plays a significant role in the regulation of cellular
redox homeostasis and other physiological or pathophysiological processes. The over …

Discrete luminescent lanthanide complexes represent a potential alternative to organic
chromophores due to their tunability of optical properties, insensitivity to photobleaching …

Objective To discuss the current available techniques for intraoperative margin assessment
in the surgical treatment of oral squamous cell carcinoma (OSCC) through a review of the …

Clear surgical margins for solid tumor resection are essential for preventing cancer
recurrence and improving overall patient survival. Complete resection of tumors is often …