NE Wondergem, IH Nauta, T Muijlwijk… - Current oncology …, 2020 - Springer
Purpose To understand why some patients respond to immunotherapy but many do not, a clear picture of the tumor microenvironment (TME) of head and neck squamous cell …
T De Bakker, F Journe, G Descamps, S Saussez… - Frontiers in …, 2022 - frontiersin.org
TP53 mutation is one of the most frequent genetic alterations in head and neck squamous cell carcinoma (HNSCC) and results in an accumulation of p53 protein in tumor cells. This …
Over the past few decades, with the rise of immunotherapies, tumor infiltrating immune cells were increasingly investigated. Indeed, they may represent biomarkers for patient outcome …
SK Bisheshar, MF van der Kamp, EJ de Ruiter… - Oral Oncology, 2022 - Elsevier
Head and neck squamous cell carcinoma (HNSCC) is an immunogenic cancer type, and tumor associated macrophages (TAMs) are a major component of the tumor …
JR Lechien, G Descamps, I Seminerio, S Furgiuele… - Cancers, 2020 - mdpi.com
Head and neck squamous cell carcinomas (HNSCC) are one of the most prevalent cancers worldwide. Active human papillomavirus (HPV) infection has been identified as an important …
M Toulmonde, C Lucchesi, S Verbeke, A Crombe… - …, 2020 - thelancet.com
Background Undifferentiated pleomorphic sarcoma (UPS) is the most frequent, aggressive and less-characterized sarcoma subtype. This study aims to assess UPS molecular …
JR Lechien, I Seminerio, G Descamps, Q Mat… - Cells, 2019 - mdpi.com
Objectives: To review the current knowledge regarding the involvement of human papilloma virus (HPV) infection and the immune system in the development of head and neck …
R Baudouin, S Hans, Q Lisan, B Morin… - The …, 2024 - Wiley Online Library
Objective The immune microenvironment of HPV‐associated (HPV+) oropharyngeal squamous cell carcinomas (OPSCCs)(HPV+ OPSCCs) differs from that of HPV‐independent …
SJ Santegoets, CL Duurland… - … for ImmunoTherapy of …, 2020 - ncbi.nlm.nih.gov
Background Human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC) is a distinct clinical entity with a much better prognosis after (chemo) …