Lysine acetylation is a widespread and versatile protein post-translational modification.
Lysine acetyltransferases and lysine deacetylases catalyse the addition or removal …

Ferroptosis is a novel form of iron-dependent cell death characterized by lipid peroxidation.
While the importance and disease relevance of ferroptosis is gaining recognition, much …

Recurrent breast cancer presents significant challenges with aggressive phenotypes and
treatment resistance. Therefore, novel therapeutics are urgently needed. Here, we report …

The fusion of autophagosomes and endosomes/lysosomes, also called autophagosome
maturation, ensures the degradation of autophagic cargoes. It is an important regulatory step …

All organisms exposed to metabolic and environmental stresses have developed various
stress adaptive strategies to maintain homeostasis. The main bacterial stress survival …

Abstract Ninjurin-1 (NINJ1), initially identified as a stress-induced protein in neurons,
recently emerged as a key mediator of plasma membrane rupture (PMR) during apoptosis …

The transition from mitosis to interphase, referred to as mitotic exit, is a critical mitotic
process which involves activation and inactivation of multiple mitotic kinases and …

Coenzyme A (CoA) is a vital and ubiquitous cofactor required in a vast number of enzymatic
reactions and cellular processes. To date, four rare human inborn errors of CoA biosynthesis …

Despite the increasing use of protoplasts in plant biotechnology research, shoot
regeneration from protoplasts remains challenging. In this study, we investigated the factors …

Epilepsy is a common and severe chronic neurological disorder. Recently, post-translational
modification (PTM) mechanisms, especially protein acetylation modifications, have been …