Intravital microscopy is increasingly used to visualize and quantitate dynamic biological
processes at the (sub) cellular level in live animals. By visualizing tissues through imaging …

Non-invasive measurement of drug-target engagement can provide critical insights in the
molecular pharmacology of small molecule drugs. Fluorescence polarization/fluorescence …

Stable, high-resolution intravital imaging of the lung has become possible through the
utilization of vacuum-stabilized imaging windows. However, this technique is extremely …

BACKGROUND: Chronic mental stress accelerates atherosclerosis through complicated
neuroimmune pathways, needing for advanced imaging techniques to delineate underlying …

Nonlinear optical imaging (NLOI) has emerged to be a promising tool for bio-medical
imaging in recent times. Among the various applications of NLOI, its utility is the most …

Neuroimaging has become an unparalleled tool to understand the central nervous system
(CNS) anatomy, physiology and neurological diseases. While an altered immune function …

Intravital imaging is an invaluable tool for understanding the function of cells in healthy and
diseased tissues. It provides a window into dynamic processes that cannot be studied by …

Since its invention 29 years ago, two‐photon laser‐scanning microscopy has evolved from a
promising imaging technique, to an established widely available imaging modality used …

The growth and development of optical components and, in particular, the miniaturization of
micro-electro-mechanical systems (MEMSs), has motivated and enabled researchers to …

Molecular mobility, localisation and spatiotemporal activity are at the core of cell biological
processes and deregulation of these dynamic events can underpin disease development …