Data derived principally from peripheral tissues (fat, muscle and liver) show that insulin
signals via diverse interconnecting intracellular pathways and that some of the major …

FOS, a subunit of the activator protein-1 (AP-1) transcription factor, has been implicated in
various cellular changes. In the human ovary, the expression of FOS and its heterodimeric …

Follicular fluid (FF) acts as a vehicle for paracrine signalling between somatic cells of the
follicle and the oocyte. To investigate changes in the protein composition of FF during …

Assisted reproductive technologies are an emerging field in equine reproduction, with
species-dependent peculiarities, such as the low success rate of conventional IVF. Here, the …

Background Estrogen receptor beta (ERβ, Esr2) plays a pivotal role in folliculogenesis and
ovulation, yet its exact mechanism of action is mainly uncharacterized. Results We here …

The ovulatory luteinizing hormone (LH) surge induces rapid changes of gene expression
and cellular functions in granulosa cells (GCs) undergoing luteinization. However, it remains …

Glucose is an essential source of energy production for animal cells. The importance of
glucose metabolism in oocyte maturation has been studied extensively in mammals …

During ovulation, the apical wall of the preovulatory follicle breaks down to facilitate gamete
release. In parallel, the residual follicle wall differentiates into a progesterone-producing …

The pituitary gonadotropin luteinizing hormone (LH) is the primary stimulus for ovulation,
luteal formation, and progesterone synthesis, regardless of species. Despite increased …

Introduction: Oocytes and follicular somatic cells within the ovarian follicle are altered during
maturation and after exposure to culture in vitro. In the present study, we used a nontargeted …