Evaluating ultraviolet sensitivity of adventitious agents in biopharmaceutical manufacturing

SM Meunier, MR Sasges… - Journal of Industrial …, 2017 - academic.oup.com
Incidents of contamination in biopharmaceutical production have highlighted the need to
apply alternative or supplementary disinfection techniques. Ultraviolet (UV) irradiation is a …

Portable analytical techniques for monitoring volatile organic chemicals in biomanufacturing processes: recent advances and limitations

X Chen, R Hu, L Hu, Y Huang, W Shi, Q Wei… - Frontiers in …, 2020 - frontiersin.org
It is essential to develop effective analytical techniques for accurate and continuous
monitoring of various biomanufacturing processes, such as the production of monoclonal …

[HTML][HTML] Long-term ultraviolet treatment for macrofouling control in northern and southern hemispheres

P Whitworth, AS Clare, JA Finlay, RF Piola… - Journal of Marine …, 2023 - mdpi.com
The biofouling of marine structures must be controlled if crippling operational and
maintenance costs are to be avoided and biological invasions prevented. However …

Design of novel tricaprylin-incorporated multi-layered liposomal system for skin delivery of ascorbic acid with improved chemical stability

MJ Ho, DW Park, MJ Kang - Pharmaceuticals, 2023 - mdpi.com
L-ascorbic acid (Vit C) possesses a variety of dermatological functions in maintaining skin
health and anti-aging properties. However, its topical application is challenging owing to its …

Protection of biomanufacturing processes from virus contamination through upstream virus filtration of cell culture media

A Wieser, J Modrof, TR Kreil - Biotechnology and …, 2023 - Wiley Online Library
Cell‐based manufacturing processes have occasionally been exposed to adventitious
viruses, leading to manufacturing interruptions and unstable supply situations. The rapid …

Toward better understanding vacuum ultraviolet—iodide induced photolysis via hydrogen peroxide formation, iodine species change, and difluoroacetic acid …

Y Yang, Q Zhang, B Chen, L Long, G Zhang - Frontiers of Environmental …, 2022 - Springer
Recently, a photochemical process induced by ultraviolet (UV), vacuum UV (VUV), and
iodide (I−) has gained attention for its robust potential for contaminant degradation …

Monitoring of heat-and light exposure of cell culture media by RAMAN spectroscopy: Towards an analytical tool for cell culture media quality control

P Mayrhofer, D Reinhart, A Castan, R Kunert - Biochemical Engineering …, 2021 - Elsevier
Cell culture media are highly complex solutions of multiple nutrients for mammalian cells
and lay the foundation for enhanced quality of the expressed protein and the performance of …

[HTML][HTML] Novel Exosomal miRNA Expression in Irradiated Human Keratinocytes

H Almujally, N Abuharfeil… - International Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
The epidermis, the outer layer of the skin, relies on a delicate balance of cell growth and
keratinocyte differentiation for its function and renewal. Recent research has shed light on …

Considerations for risk and control of mycoplasma in bioprocessing

P Angart, C Kohnhorst, MJ Chiang, NS Arden - Current opinion in chemical …, 2018 - Elsevier
Highlights•Mycoplasmas continue to pose risks to bioprocessing operations and product
quality.•The size and structure of mycoplasma allow them to evade 0.1 μm sterile …

Marine Biofouling Control by Ultraviolet Light: Development, Ecological Impact and Genomic Assessment

P Whitworth - 2023 - theses.ncl.ac.uk
Biofouling is an issue for any surface within the marine environment, causing environmental
and financial ramifications. The harmful effects of ultraviolet (UV) light have been well …