Malaria is a vector-borne parasitic disease caused by the apicomplexan protozoan parasite
Plasmodium. Malaria is a significant health problem and the leading cause of …

Antimalarial drugs have usually been first deployed in areas of malaria endemicity at doses
which were too low, particularly for high-risk groups such as young children and pregnant …

Background Planning and evaluating malaria control strategies relies on accurate definition
of parasite prevalence in the population. A large proportion of asymptomatic parasite …

The epidemiology of malaria in “low-transmission” areas has been underestimated.
Molecular detection methods have revealed higher prevalences of malaria than …

Background. Three full doses of RTS, S/AS01 malaria vaccine provides partial protection
against controlled human malaria parasite infection (CHMI) and natural exposure …

Background The importance of the submicroscopic reservoir of Plasmodium infections for
malaria elimination depends on its size, which is generally considered small in low …

Background The emergence and spread of multidrug-resistant Plasmodium falciparum in
the Greater Mekong Subregion (GMS) threatens global malaria elimination efforts. Mass …

Background A substantial proportion of Plasmodium species infections are asymptomatic
with densities too low to be detectable with standard diagnostic techniques. The importance …

We describe development of an absolute multiplex quantitative real-time PCR for detection
of Plasmodium spp., P. falciparum and P. vivax targets in order to produce an assay …

Acute febrile illness (AFI) is associated with substantial morbidity and mortality worldwide,
yet an etiologic agent is often not identified. Convalescent-phase serology is impractical …