Carica papaya: comprehensive overview of the nutritional values, phytochemicals and pharmacological activities

OR Alara, NH Abdurahman, JA Alara - Advances in traditional medicine, 2020 - Springer
Carica papaya is a perennial large herbaceous plant known for diverse biological activities.
Different parts of this plant such as seeds, leaves, fruits, peels, roots, and stems have been …

Anticancer activities of dietary benzyl isothiocyanate: A comprehensive review

TN Dinh, MO Parat, YS Ong, KY Khaw - Pharmacological Research, 2021 - Elsevier
Benzyl isothiocyanate (BITC) is one of the common isothiocyanates found in cruciferous
vegetables such as broccoli, cabbage or watercress. Preclinical studies report of its …

The effects of ellagic acid and other pomegranate (Punica granatum L.) derivatives on human gastric cancer AGS cells

H Cheshomi, AR Bahrami… - Human & …, 2022 - journals.sagepub.com
Although surgery with or without (neo) adjuvant chemo/radiotherapy, as the standard
treatments, can be suitable therapeutic strategies for gastric cancer, side effects and drug …

Anticancer activity of Carica papaya: A review

TTT Nguyen, PN Shaw, MO Parat… - Molecular nutrition & …, 2013 - Wiley Online Library
C arica papaya is widely cultivated in tropical and subtropical countries and is used as food
as well as traditional medicine to treat a range of diseases. Increasing anecdotal reports of …

Dietary isothiocyanates inhibit cancer progression by modulation of epigenome

MK Sundaram, R Preetha, S Haque, N Akhter… - Seminars in Cancer …, 2022 - Elsevier
Cell cycle, growth, survival and metabolism are tightly regulated together and failure in
cellular regulation leads to carcinogenesis. Several signaling pathways like the PI3K, WNT …

Structure-based classification and anti-cancer effects of plant metabolites

SA Shin, SY Moon, WY Kim, SM Paek, HH Park… - International journal of …, 2018 - mdpi.com
A variety of malignant cancers affect the global human population. Although a wide variety of
approaches to cancer treatment have been studied and used clinically (surgery …

Natural isothiocyanates: genotoxic potential versus chemoprevention

C Fimognari, E Turrini, L Ferruzzi, M Lenzi… - … Research/Reviews in …, 2012 - Elsevier
Isothiocyanates, occurring in many dietary cruciferous vegetables, show interesting
chemopreventive activities against several chronic–degenerative diseases, including …

Cruciferous vegetable consumption and gastric cancer risk: A meta‐analysis of epidemiological studies

QJ Wu, Y Yang, J Wang, LH Han, YB Xiang - Cancer science, 2013 - Wiley Online Library
The relationship between consumption of cruciferous vegetables (CV) and risk of gastric
cancer has been investigated by many studies, but remains controversial. We carried out a …

Benzyl Isothiocyanate Attenuates Inflammasome Activation in Pseudomonas aeruginosa LPS-Stimulated THP-1 Cells and Exerts Regulation through the MAPKs/NF …

WS Park, J Lee, G Na, SG Park, SK Seo… - International Journal of …, 2022 - mdpi.com
Inflammasomes are a group of intracellular multiprotein platforms that play important roles in
immune systems. Benzyl isothiocyanate (BITC) is a constituent of cruciferous plants and has …

Mechanisms and functions of chemerin in cancer: potential roles in therapeutic intervention

WJ Shin, BA Zabel, RK Pachynski - Frontiers in immunology, 2018 - frontiersin.org
Chemerin [RARRES2 [retinoic acid receptor responder 2], TIG2 [tazarotene induced gene 2
(TIG2)]] is a multifunctional cytokine initially described in skin cultures upon exposure to the …