[HTML][HTML] Phytochemicals: Current strategy to sensitize cancer cells to cisplatin

CY Sun, QY Zhang, GJ Zheng, B Feng - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Cisplatin-based chemotherapeutic regimens are the most frequently used adjuvant
treatments for many types of cancer. However, the development of chemoresistance to …

Pro-inflammatory signalling PRRopels cisplatin-induced toxicity

IK Domingo, A Latif, AP Bhavsar - International journal of molecular …, 2022 - mdpi.com
Cisplatin is a platinum-based chemotherapeutic that has long since been effective against a
variety of solid-cancers, substantially improving the five-year survival rates for cancer …

The protective effects of hesperidin and curcumin on 5-fluorouracil–induced nephrotoxicity in mice

V Gelen, E Şengül, S Yıldırım, E Senturk… - … Science and Pollution …, 2021 - Springer
Nephrotoxicity is a very important complication of 5-fluorouracil (5-FU)–treated cancer
patients. Increased oxidative stress, kidney damage, and apoptosis play an important role in …

The protective effect of crocin on cisplatin-induced testicular impairment in rats

B Mesbahzadeh, M Hassanzadeh-Taheri, M Aliparast… - Bmc Urology, 2021 - Springer
Background Side effects of cisplatin (CIS) such as testicular toxicity restrict its clinical use.
Instead, evidence indicates that crocin (CR) has synergistic anti-cancer potential with CIS …

Ethanolic Extract of Moringa oleifera Leaves Influences NF-κB Signaling Pathway to Restore Kidney Tissue from Cobalt-Mediated Oxidative Injury and Inflammation …

MM Abdel-Daim, SR Khalil, A Awad, EH Abu Zeid… - Nutrients, 2020 - mdpi.com
This study aimed to describe the protective efficacy of Moringa oleifera ethanolic extract
(MOEE) against the impact of cobalt chloride (CoCl2) exposure on the rat's kidney. Fifty male …

Eugenol attenuates TiO2 nanoparticles-induced oxidative damage, biochemical toxicity and DNA damage in Wistar rats: an in vivo study

MR Wani, N Maheshwari, G Shadab - Environmental Science and …, 2021 - Springer
Abstract Titanium dioxide nanoparticles (TiO 2 NPs) are widely used in food, edible dyes,
and other commercial products. Human exposure to TiO 2 NPs has raised concerns …

The antiapoptotic and antioxidant effects of eugenol against cisplatin‐induced testicular damage in the experimental model

FN Ekinci Akdemir, S Yildirim, FM Kandemir… - Andrologia, 2019 - Wiley Online Library
Testicular dysfunction or damage is among the critical side effects of chemotherapeutic
drugs like cisplatin. This study was mapped out to assess the possible therapeutic effect of …

[HTML][HTML] The protective effect and potential mechanisms of eugenol against Salmonella in vivo and in vitro

X Zhao, SM Zheng, SM Wei, QM Tian, Y Tao, RN Bo… - Poultry Science, 2022 - Elsevier
Salmonella enterica serovar Typhimurium (S. Typhimurium) continues to be a serious
concern to the poultry industry as a bacterial foodborne zoonosis, which generally results in …

Effects of natural products on cisplatin ototoxicity and chemotherapeutic efficacy

LP Rybak, I Alberts, S Patel… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Cisplatin is a very effective chemotherapeutic agent against a variety of solid
tumors. Unfortunately, cisplatin causes permanent sensorineural hearing loss in at least two …

Strategies to reduce the risk of platinum containing antineoplastic drug-induced ototoxicity

D Mukherjea, A Dhukhwa, A Sapra… - Expert opinion on …, 2020 - Taylor & Francis
Introduction Cisplatin is a highly effective chemotherapeutic agent against a variety of solid
tumors in adults and in children. Unfortunately, a large percentage of patients suffer …