Shortening synthetic routes to small molecule active pharmaceutical ingredients employing biocatalytic methods

S Simić, E Zukić, L Schmermund, K Faber… - Chemical …, 2021 - ACS Publications
Biocatalysis, using enzymes for organic synthesis, has emerged as powerful tool for the
synthesis of active pharmaceutical ingredients (APIs). The first industrial biocatalytic …

Biomass-based biorefineries: an important architype towards a circular economy

B Kumar, P Verma - Fuel, 2021 - Elsevier
Fossil based resources are a major contributor to energy and chemicals to modern-day
development. The negative environmental impacts of fossil-based resources accompanied …

Biodiesel production from microalgae using lipase-based catalysts: current challenges and prospects

GF Mota, IG de Sousa, ALB de Oliveira… - Algal Research, 2022 - Elsevier
The excessive demand for fossil fuels has caused severe environmental impacts, such as
GHG-related effects and widespread pollution. Firstly, it is essential to identify the main …

Large-scale production of enzymes for biotechnology uses

A Fasim, VS More, SS More - Current opinion in biotechnology, 2021 - Elsevier
Enzymes are biocatalysts that speed up the chemical reaction to obtain the final valuable
product/s. Biotechnology has revolutionized the use of traditional enzymes to be applicable …

Renewable polyurethanes from sustainable biological precursors

TA Phung Hai, M Tessman, N Neelakantan… - …, 2021 - ACS Publications
Due to the depletion of fossil fuels, higher oil prices, and greenhouse gas emissions, the
scientific community has been conducting an ongoing search for viable renewable …

Recent advances in biocatalysis with chemical modification and expanded amino acid alphabet

AD Pagar, MD Patil, DT Flood, TH Yoo… - Chemical …, 2021 - ACS Publications
The two main strategies for enzyme engineering, directed evolution and rational design,
have found widespread applications in improving the intrinsic activities of proteins. Although …

Getting the Most Out of Enzyme Cascades: Strategies to Optimize In Vitro Multi-Enzymatic Reactions

R Siedentop, C Claaßen, D Rother, S Lütz… - Catalysts, 2021 - mdpi.com
In vitro enzyme cascades possess great benefits, such as their synthetic capabilities for
complex molecules, no need for intermediate isolation, and the shift of unfavorable equilibria …

Integrated strategies for enzyme assisted extraction of bioactive molecules: A review

S Das, SS Nadar, VK Rathod - International Journal of Biological …, 2021 - Elsevier
Conventional methods of extracting bioactive molecules are gradually losing pace due to
their numerous disadvantages, such as product degradation, lower efficiency, and toxicity …

Current challenges of biomass refinery and prospects of emerging technologies for sustainable bioproducts and bioeconomy

A Asghar, S Sairash, N Hussain, Z Baqar… - Biofuels, Bioproducts …, 2022 - Wiley Online Library
The depletion of fossil resources and the resulting global warming are the primary
motivators for moving from a fossil‐based to a biobased economy. Biorefineries, like petro …

Bioprospecting of novel extremozymes from prokaryotes—The advent of culture-independent methods

M Sysoev, SW Grötzinger, D Renn, J Eppinger… - Frontiers in …, 2021 - frontiersin.org
Extremophiles are remarkable organisms that thrive in the harshest environments on Earth,
such as hydrothermal vents, hypersaline lakes and pools, alkaline soda lakes, deserts, cold …