Paclitaxel in cancer treatment: perspectives and prospects of its delivery challenges

S Singh, AK Dash - Critical Reviews™ in Therapeutic Drug …, 2009 - dl.begellhouse.com
Paclitaxel (PTX) is a potent anticancer agent whose clinical usefulness is marred by a
delivery problem that is caused by its unfavorable pharmacokinetic and physical properties …

Cancer-testis antigens in ovarian cancer: implication for biomarkers and therapeutic targets

K Xie, C Fu, S Wang, H Xu, S Liu, Y Shao… - Journal of ovarian …, 2019 - Springer
Ovarian cancer remains the most fatal gynecologic malignancy worldwide due to delayed
diagnosis as well as recurrence and drug resistance. Thus, the development of new tumor …

Crystal structures of MHC class I complexes reveal the elusive intermediate conformations explored during peptide editing

L Li, X Peng, M Batliwala, M Bouvier - Nature Communications, 2023 - nature.com
Studies have suggested that MHC class I (MHC I) molecules fluctuate rapidly between
numerous conformational states and these motions support peptide sampling. To date, MHC …

RACK1 affects glioma cell growth and differentiation through the CNTN2-mediated RTK/Ras/MAPK pathway

Y Yan, Y Jiang - International Journal of Molecular …, 2016 - spandidos-publications.com
Receptor for activated C kinase 1 (RACK1) and contactin-2 (CNTN2) are known to be
abnormally expressed in gliomas; however, the association between RACK1 and CNTN2 …

Expression of cancer/testis antigens in cutaneous melanoma: a systematic review

D Tio, FR Kasiem, M Willemsen, R van Doorn… - Melanoma …, 2019 - journals.lww.com
The cancer/testis antigen (CTA) family is a group of antigens whose expression is restricted
to male germline cells of the testis and various malignancies. This expression pattern makes …

Epigenetic modulation to enable antigen-specific T-cell therapy of colorectal cancer

J Chou, LN Voong, CL Mortales… - Journal of …, 2012 - journals.lww.com
Abstract Development of specific immunotherapy for colorectal cancer (CRC) will require
identification of antigens selectively or exclusively expressed on CRC cells and strategies to …

Therapeutic cancer vaccines—antigen discovery and adjuvant delivery platforms

NO Alarcon, M Jaramillo, HM Mansour, B Sun - Pharmaceutics, 2022 - mdpi.com
For decades, vaccines have played a significant role in protecting public and personal
health against infectious diseases and proved their great potential in battling cancers as …

Identification of differential splicing genes in gliomas using exon expression profiling

F Yu, WM Fu - Molecular medicine reports, 2015 - spandidos-publications.com
Diffuse gliomas are the most common type of malignant primary brain tumor, and their
initiation and/or progression are often associated with alternative splicing. They produce an …

The potential value of cancer‐testis antigens in ovarian cancer: Prognostic markers and targets for immunotherapy

L Lin, X Zou, W Nong, Y Ge, F Li, B Luo… - Immunity …, 2024 - Wiley Online Library
Background Tumor immunotherapy has become an important adjuvant therapy after
surgery, radiotherapy, and chemotherapy. In recent years, the role of tumor‐associated …

[HTML][HTML] Cancer-testis antigens: a novel group of tumor biomarkers in ovarian cancers

Z Taherian-Esfahani, A Abedin-Do… - Iranian journal of …, 2016 - brieflands.com
Context: Ovarian cancer is the most fatal gynecological malignancy with no effective
screening strategy for early detection. As most cases are being detected in advance stages …