Cytochrome P450 (CYP) enzymes are frequently referred to as the third pathway for the
metabolism of arachidonic acid. While it is true that these enzymes generate arachidonic …

Cancer therapy, including immunotherapy, is inherently limited by chronic inflammation-
induced tumorigenesis and toxicity within the tumor microenvironment. Thus, stimulating the …

Chemical exposure can profoundly affect our health, some being voluntary (food and drugs)
and some involuntary (environmental contaminants). The metabolism of these chemicals is …

The lipid content of skin plays a determinant role in its barrier function with a particularly
important role attributed to linoleic acid and its derivatives. Here we explored the …

Breast cancer (BC) is the most common cancer in women, with incidence rates increasing
globally in recent years. Therefore, it is important to find new molecules with prognostic and …

目的: 运用生物信息学及细胞实验方法研究大黄素治疗胰腺癌的靶点. 方法:
从基因表达综合数据库(GEO) 获取胰腺癌转录组数据集GSE62452, GSE28753 …

Uveal melanoma is the primary form of eye cancer–a rare but deadly disease with up to 50%
of the patients' died from metastasis. Patients with metastatic UM have a lifespan of up to 18 …

Günümüzde kronik hastalıkların sıklığının artması; hastada yaşam kalitesinin düşmesi, erken
ölümlerin görülmesi gibi durumlara sebep olurken aynı zamanda sağlık sistemi ve topluma …

Background This exploratory study aimed to investigate whether dexmedetomidine,
propofol, sevoflurane, and S-ketamine affect oxylipins and bile acids, which are functionally …