Trends in formulation approaches for sustained drug delivery to the posterior segment of the eye

A Biswas, AD Choudhury, AC Bisen, S Agrawal… - AAPS …, 2023 - Springer
The eye, an intricate organ comprising physical and physiological barriers, poses a
significant challenge for ophthalmic physicians seeking to treat serious ocular diseases …

Ionic liquids: momentous tools in transdermal delivery of biomacromolecules

L Li, Z Tai, X Wu, J Wu, T Zhang, Z Chen… - Advanced …, 2023 - Wiley Online Library
Transdermal drug delivery is a promising strategy characterized by minor fluctuations in
blood concentrations, few adverse effects, convenience, and excellent patient compliance …

[HTML][HTML] Lipid-based nanoparticles as drug delivery carriers for cancer therapy

I Waheed, A Ali, H Tabassum, N Khatoon… - Frontiers in …, 2024 - ncbi.nlm.nih.gov
Cancer is a severe disease that results in death in all countries of the world. A nano-based
drug delivery approach is the best alternative, directly targeting cancer tumor cells with …

[HTML][HTML] Thin-film nanofibers for treatment of age-related macular degeneration

A Garkal, P Bangar, T Mehta - OpenNano, 2022 - Elsevier
AMD is the leading cause of blindness and is found in elderly patients. Lutein is a carotenoid
and has antioxidant properties hence acting as a neuroprotective in the macular region …

Long‐Acting Ocular Injectables: Are We Looking In The Right Direction?

M Dang, MS Shoichet - Advanced Science, 2024 - Wiley Online Library
The complex anatomy and physiological barriers of the eye make delivering ocular
therapeutics challenging. Generally, effective drug delivery to the eye is hindered by rapid …

[HTML][HTML] Multifunctional nano-in-micro delivery systems for targeted therapy in fundus neovascularization diseases

X Liu, K Huang, F Zhang, G Huang, L Wang… - Journal of …, 2024 - Springer
Fundus neovascularization diseases are a series of blinding eye diseases that seriously
impair vision worldwide. Currently, the means of treating these diseases in clinical practice …

[HTML][HTML] Global research trends and future directions in diabetic macular edema research: A bibliometric and visualized analysis

Y Li, C Jie, J Wang, W Zhang, J Wang, Y Deng, Z Liu… - Medicine, 2024 - journals.lww.com
Background: Diabetic Macular Edema (DME) significantly impairs vision in diabetics, with
varied patient responses to current treatments like anti-vascular endothelial growth factor …

Long-Acting Strategies for Antibody Drugs: Structural Modification, Controlling Release, and Changing the Administration Route

H Wang, M Song, J Xu, Z Liu, M Peng, H Qin… - European Journal of …, 2024 - Springer
Because of their high specificity, high affinity, and targeting, antibody drugs have been
widely used in the treatment of many diseases and have become the most favored new …

Preclinical modeling of intravitreal suspensions

S Castleberry - International Journal of Pharmaceutics, 2023 - Elsevier
There are a number of obstacles that complicate the development of intravitreal delivered
small molecules therapies. One serious complication is the potential need for complex …