How does hemodynamics affect rupture tissue mechanics in abdominal aortic aneurysm: Focus on wall shear stress derived parameters, time-averaged wall shear …

O Mutlu, HE Salman, H Al-Thani, A El-Menyar… - Computers in biology …, 2023 - Elsevier
An abdominal aortic aneurysm (AAA) is a critical health condition with a risk of rupture,
where the diameter of the aorta enlarges more than 50% of its normal diameter. The …

[HTML][HTML] Computational methods for fluid-structure interaction simulation of heart valves in patient-specific left heart anatomies

TB Le, M Usta, C Aidun, A Yoganathan, F Sotiropoulos - Fluids, 2022 - mdpi.com
Given the complexity of human left heart anatomy and valvular structures, the fluid–structure
interaction (FSI) simulation of native and prosthetic valves poses a significant challenge for …

An ultrasound-exclusive non-invasive computational diagnostic framework for personalized cardiology of aortic valve stenosis

N Bahadormanesh, B Tomka, M Kadem… - Medical Image …, 2023 - Elsevier
Aortic stenosis (AS) is an acute and chronic cardiovascular disease and If left untreated,
50% of these patients will die within two years of developing symptoms. AS is characterized …

Extracting Lagrangian coherent structures in cardiovascular flows using Lagrangian descriptors

A Darwish, S Norouzi, G Di Labbio, L Kadem - Physics of Fluids, 2021 - pubs.aip.org
In cardiovascular flows, Lagrangian coherent structures have been used to explore the
skeleton of blood transport. Revealing these transport barriers is instrumental to quantify the …

[HTML][HTML] A Doppler-exclusive non-invasive computational diagnostic framework for personalized transcatheter aortic valve replacement

N Bahadormanesh, B Tomka, M Abdelkhalek… - Scientific Reports, 2023 - nature.com
Given the associated risks with transcatheter aortic valve replacement (TAVR), it is crucial to
determine how the implant will affect the valve dynamics and cardiac function, and if TAVR …

Three-dimensional Lagrangian coherent structures in patients with aortic regurgitation

W Abdallah, A Darwish, J Garcia, L Kadem - Physics of Fluids, 2024 - pubs.aip.org
Understanding blood transport in cardiovascular flows is important for managing patients
with cardiovascular disease. In this study, three-dimensional Lagrangian coherent structures …

Fluid-structure interaction simulation of calcified aortic valve stenosis

L Cai, Y Hao, P Ma, G Zhu, X Luo… - Mathematical Biosciences …, 2022 - eprints.gla.ac.uk
Calcified aortic valve stenosis (CAVS) is caused by calcium buildup and tissue thickening
that impede the blood flow from left ventricle (LV) to aorta. In recent years, CAVS has …

[HTML][HTML] Hemodynamic and structural comparison of human fetal heart development between normally growing and hypoplastic left heart syndrome-diagnosed hearts

HE Salman, RY Kamal, ZM Hijazi, HC Yalcin - Frontiers in Physiology, 2022 - frontiersin.org
Congenital heart defects (CHDs) affect a wide range of societies with an incidence rate of
1.0–1.2%. These defects initiate at the early developmental stage and result in critical health …

[HTML][HTML] Smoothed particle hydrodynamics based FSI simulation of the native and mechanical heart valves in a patient-specific aortic model

S Laha, G Fourtakas, PK Das, A Keshmiri - Scientific Reports, 2024 - nature.com
The failure of the aortic heart valve is common, resulting in deterioration of the pumping
function of the heart. For the end stage valve failure, bi-leaflet mechanical valve (most …

Computational fluid–structure analysis of the impact of leaflet thickness and protrusion height on the flutter phenomenon in aortic valve bioprostheses

MCB Costa, SF Gonçalves, JVC Fleury, MLF Silva… - Meccanica, 2024 - Springer
Although it is associated with the low lifetime of aortic valve bioprostheses, flutter has little
been studied in the dynamics of these valves. To improve the understanding of flutter in …