Prediction of acute toxicity for Chlorella vulgaris caused by tire wear particle-derived compounds using quantitative structure-activity relationship models
JR Jiang, WX Cai, ZF Chen, XL Liao, Z Cai - Water Research, 2024 - Elsevier
Tire wear particles (TWPs) enter aquatic ecosystems through various pathways, such as
rainwater and urban runoff. Additives in TWPs can harm aquatic organisms in these …
rainwater and urban runoff. Additives in TWPs can harm aquatic organisms in these …
Innovative screening for functional improved aromatic amine derivatives: Toxicokinetics, free radical oxidation pathway and carcinogenic adverse outcome pathway
Y Liu, X Li, Q Pu, R Fu, Z Wang, Y Li, X Li - Journal of Hazardous Materials, 2023 - Elsevier
Aromatic amines, one of the most widely used low-cost antioxidants in rubbers, have been
regarded as pollutants with human health concerns. To overcome this problem, this study …
regarded as pollutants with human health concerns. To overcome this problem, this study …
Identification of a 1, 8-naphthyridine-containing compound endowed with the inhibition of p53-MDM2/X interaction signaling: a computational perspective
OF Olukunle, CB Olowosoke, A Khalid, GA Oke… - Molecular Diversity, 2023 - Springer
Various studies have established that molecules specific for MDMX inhibition or optimized
for dual inhibition of p53-MDM2/MDMX interaction signaling are more suitable for activating …
for dual inhibition of p53-MDM2/MDMX interaction signaling are more suitable for activating …
Screening of compounds from Nigerian antidiabetic plants as protein tyrosine phosphatase 1B inhibitor
Several studies have established the antidiabetic properties of several traditional Nigerian
plants, but only limited studies have elucidated their mechanism of action. Protein tyrosine …
plants, but only limited studies have elucidated their mechanism of action. Protein tyrosine …
Cooperativity of ESPT and aggregation-induced emission effects—an experimental and theoretical analysis of a 1, 3, 4-thiadiazole derivative
I Budziak-Wieczorek, D Kaczmarczyk, K Rząd… - International Journal of …, 2024 - mdpi.com
4-[5-(Naphthalen-1-ylmethyl)-1, 3, 4-thiadiazol-2-yl] benzene-1, 3-diol (NTBD) was
extensively studied through stationary UV–vis absorption and fluorescence measurements …
extensively studied through stationary UV–vis absorption and fluorescence measurements …
Structural effects of sulfonamides on the proliferation dynamics of sulfonamide resistance genes in the sequencing batch reactors and the mechanism
L Wu, M Wang, L Rong, W Wang, L Chen, Q Wu… - Journal of …, 2024 - Elsevier
Antibiotic resistance genes (ARGs) can be easily promoted by antibiotics, however, the
structural effects of antibiotics on the proliferation of ARGs dynamic and the associated …
structural effects of antibiotics on the proliferation of ARGs dynamic and the associated …
[HTML][HTML] Integrative study of phytochemicals for anti-fibroid agent: A perspective on protein networks, molecular docking, ADMET, simulation, DFT and bioactivity
CB Olowosoke, CJ Eze, A Munir, OO Dada… - Chemical Physics …, 2024 - Elsevier
Purpose Beyond the pains of pregnancy, miscarriages and other child-bearing risks
associated with the pride of motherhood, Uterine fibroids (UFs) are another significant …
associated with the pride of motherhood, Uterine fibroids (UFs) are another significant …
Discovery of putative inhibitors against main drivers of SARS-CoV-2 infection: Insight from quantum mechanical evaluation and molecular modeling
SARS-CoV-2 triggered a worldwide medical crisis, affecting the world's social, emotional,
physical, and economic equilibrium. However, treatment choices and targets for finding a …
physical, and economic equilibrium. However, treatment choices and targets for finding a …
Modulating the immunosuppressive tumor microenvironment: Multi-synergistic cancer therapeutic approach with oncolytic viruses
Most patients with complex malignancies show a high level of toxicity and limited long-
lasting responses to current conventional therapies. In contrast, the immune system has the …
lasting responses to current conventional therapies. In contrast, the immune system has the …
MiR-450b-5p enhances the radiosensitivity of HR+ and HER2− breast cancer by targeting CDK6
RX Wu, HW Zhang, XY Huang… - Oncology and …, 2024 - journals.lww.com
Background The sensitivity of breast cancer cells to radiation is a key cause of locoregional
recurrence after postoperative radiotherapy. Several studies have reported that microRNAs …
recurrence after postoperative radiotherapy. Several studies have reported that microRNAs …