After 15 years of global scale-up of antiretroviral therapy (ART), rising prevalence of HIV
drug resistance in many low-income and middle-income countries (LMICs) poses a growing …

Abstract Background In sub-Saharan Africa, 25.5 million people are living with human
immunodeficiency virus (HIV), representing 70% of the global total. The need for second-line …

Background The widespread use of the integrase strand transfer inhibitor (INSTI)
dolutegravir in first-line and second-line antiretroviral therapy (ART) might facilitate …

Background As countries move towards the UNAIDS's 95-95-95 targets and with strong
evidence that undetectable equals untransmittable, it is increasingly important to assess …

Background The integrase inhibitor dolutegravir could have a major role in future
antiretroviral therapy (ART) regimens in sub-Saharan Africa because of its high potency and …

Purpose The objectives of the International epidemiology databases to evaluate AIDS
(IeDEA) are to (i) evaluate the delivery of combination antiretroviral therapy (ART) in …

Objectives Limited availability of viral load (VL) monitoring in HIV treatment programmes in
sub-Saharan Africa can delay switching to second-line ART, leading to the accumulation of …

Background The number of patients in need of second-line antiretroviral drugs is increasing
in sub-Saharan Africa. We aimed to project the need of second-line antiretroviral therapy in …

Background In 2016, we conducted a systematic review to assess the feasibility of treatment
monitoring for people living with HIV (PLHIV) receiving antiretroviral therapy (ART) in low …

Introduction: Routinely monitoring the HIV viral load (VL) of people living with HIV (PLHIV)
on anti-retroviral therapy (ART) facilitates intensive adherence counselling and faster ART …