Sleep spindles are burstlike signals in the electroencephalogram (EEG) of the sleeping
mammalian brain and electrical surface correlates of neuronal oscillations in thalamus. As …

Intracellular recordings in vivo have shown that neocortical neurons are subjected to an
intense synaptic bombardment in intact networks and are in a'high-conductance'state. In …

Deep brain stimulation (DBS) is an effective therapy for medically refractory movement
disorders. However, fundamental questions remain about the effects of DBS on neurons …

All thalamic relay cells exhibit two distinct response modes–tonic and burst–that reflect the
status of a voltage-dependent, intrinsic membrane conductance. Both response modes …

Communication between neurons in the brain occurs primarily through synapses made onto
elaborate treelike structures called dendrites. New electrical and optical recording …

During relaxed wakefulness, the human brain exhibits pronounced rhythmic electrical
activity in the α frequency band (8-13 Hz). This activity consists of 3 main components: the …

This article addresses the functional significance of the electrophysiological properties of
thalamic neurons. We propose that thalamocortical activity, is the product of the intrinsic …

Action potential propagation links information processing in different regions of the dendritic
tree. To examine the contribution of dendritic morphology to the efficacy of propagation …

Neurons that fire high-frequency bursts of spikes are found in various sensory systems.
Although the functional implications of burst firing might differ from system to system, bursts …

To better understand population phenomena in thalamocortical neuronal ensembles, we
have constructed a preliminary network model with 3,560 multicompartment neurons …