Background Symptomatic peripheral arterial disease (PAD) has several treatment options,
including angioplasty, stenting, exercise therapy, and bypass surgery. Atherectomy is an …

Chronic critical limb ischemia (CLI), defined as> 2 weeks of rest pain, ulcers, or tissue loss
attributed to arterial occlusive disease, is associated with great loss of both limb and life …

Critical limb ischemia, first defined in 1982, was intended to delineate a subgroup of patients
with a threatened lower extremity primarily because of chronic ischemia. It was the intent of …

BACKGROUND: A 2005 interim analysis of the Bypass versus Angioplasty in Severe
Ischaemia of the Leg (BASIL) trial showed that in patients with severe lower limb ischemia …

Objectives: A prospective, multinational randomized controlled trial (RCT) and a
complementary single-arm study evaluated the 2-year safety and effectiveness of a …

OBJECTIVES: The natural history of limbs affected by ischemic ulceration is poorly
understood. In this report, we describe the outcome of limbs with stable chronic leg ulcers …

OBJECTIVE: To determine the efficacy, safety, and long-term results, including continued
clinical improvement and limb salvage, of percutaneous transluminal angioplasty (PTA) in …

Endovascular strategies for the treatment of critical infrageniculate peripheral arterial
occlusive disease exist and are becoming the primary methodology for such lesions at many …

Objective To compare a 'bypass-surgery-first'with a 'balloon-angioplasty-
first'revascularisation strategy in patients with severe limb ischaemia (SLI) due to …

OBJECTIVE: Because of the prolonged healing time of diabetic foot ulcers, methods for
identifying ways to expedite the ulcer healing process are needed. The angiosome concept …