Chiral tertiary alcohols are an important class of organic compounds which have found wide
applications in both academia and industry. Therefore, various synthetic strategies towards …

The aza-Friedel–Crafts (aza-FC) reaction is a very powerful tool for forming C–C and C–N
bonds, based on an acid-catalyzed addition of electron-rich aromatic compounds to imines …

A quinine‐derived thiourea organocatalyst promoted the highly enantioselective addition of
naphthols and activated phenols to ketimines derived from isatins. The reaction afforded …

The catalytic asymmetric dearomatization reaction of non-functionalized arenes poses a
long-standing synthetic challenge to organic chemists because of the relative ease of …

An efficient enantioselective formal Betti reaction between phenols and diaryl ketimines
generated in situ from isoindolinone alcohols is described. In a reaction catalyzed by a chiral …

Abstract The Friedel‐Crafts alkylation (F‐CA) reaction is a special kind of carbon− carbon
bond formations, which is frequently being used for the formation of such bond in some …

An organocatalyst‐controlled site‐selectivity switchable enantioselective Friedel‐Crafts
reaction of unprotected 1‐naphthols has been established for the first time via the conjugate …

A bifunctional cinchona squaramide catalyzed enantioselective aza-Friedel–Crafts reaction
between 2-naphthols and benzothiazolimines has been developed, and a series of chiral …

Coprisidins A and B (1 and 2) were isolated from a gut-associated Streptomyces sp. in the
dung beetle Copris tripartitus. Using a combination of spectroscopic techniques, the …

Several oxindole derivatives, of natural or synthetic origin, have been identified as
medicinally appealing compounds, with a plethora of bioactivities reported. Chiral 3-hydroxy …