Subunit vaccines for Acinetobacter baumannii

N Yang, X Jin, C Zhu, F Gao, Z Weng, X Du… - Frontiers in …, 2023 - frontiersin.org
Acinetobacter baumannii is a gram-negative bacterium and a crucial opportunistic pathogen
in hospitals. A. baumannii infection has become a challenging problem in clinical practice …

Designing of multi-epitope peptide vaccine against Acinetobacter baumannii through combined immunoinformatics and protein interaction–based approaches

J Dey, SR Mahapatra, PK Singh… - Immunologic …, 2023 - Springer
Acinetobacter baumannii is one of the major pathogenic ESKAPE bacterium, which is
responsible for about more than 722,000 cases in a year, globally. Despite the alarming …

Promising Acinetobacter baumannii Vaccine Candidates and Drug Targets in Recent Years

YC Tan, C Lahiri - Frontiers in Immunology, 2022 - frontiersin.org
In parallel to the uncontrolled use of antibiotics, the emergence of multidrug-resistant
bacteria, like Acinetobacter baumannii, has posed a severe threat. A. baumannii …

Identification of Antigenic Properties of Acinetobacter baumannii Proteins as Novel Putative Vaccine Candidates Using Reverse Vaccinology Approach

T Piri-Gharaghie, A Doosti, SA Mirzaei - Applied Biochemistry and …, 2022 - Springer
Multidrug-resistant Acinetobacter baumannii (A. baumannii) infections are becoming more
prevalent all over the world. As a cost-effective and preventative method, vaccination seems …

Novel adjuvant nano-vaccine induced immune response against Acinetobacter baumannii

T Piri-Gharaghie, A Doosti, SA Mirzaei - AMB Express, 2023 - Springer
Developing adjuvant vaccines to combat rising multidrug-resistant (MDR) Acinetobacter
baumannii (A. baumannii) infections is a promising and cost-effective approach. The aim of …

[HTML][HTML] Fabrication and characterization of pcDNA3. 1 (+) location within chitosan/nanoparticles complexes for enhanced gene delivery

T Piri-Gharaghie, A Doosti… - Iranian Journal of …, 2022 - ncbi.nlm.nih.gov
Background: Chitosan nanoparticles (CSNP) are becoming a popular alternative for
delivering nucleic acids to tissues for gene transfer (gene therapy). The size and …

Artificial intelligence in accelerating vaccine development-current and future perspectives

R Kaushik, R Kant, M Christodoulides - Frontiers in Bacteriology, 2023 - frontiersin.org
Tackling antimicrobial resistance requires the development of new drugs and vaccines.
Artificial intelligence (AI) assisted computational approaches offer an alternative to the …

Modern vaccine development via reverse vaccinology to combat antimicrobial resistance

AJ Tobuse, CW Ang, KY Yeong - Life Sciences, 2022 - Elsevier
With the continuous evolution of bacteria, the global antimicrobial resistance health threat is
causing millions of deaths yearly. While depending on antibiotics as a primary treatment has …

A novel mRNA multi-epitope vaccine of Acinetobacter baumannii based on multi-target protein design in immunoinformatic approach

Y Xu, F Zhu, Z Zhou, S Ma, P Zhang, C Tan, Y Luo… - BMC genomics, 2024 - Springer
Acinetobacter baumannii is a gram-negative bacillus prevalent in nature, capable of thriving
under various environmental conditions. As an opportunistic pathogen, it frequently causes …

Characterization of exclusively non-commensal Neisseria gonorrhoeae pangenome to prioritize globally conserved and thermodynamically stable vaccine candidates …

I Mahnoor, H Shabbir, S Nawaz, K Aziz, U Aziz… - Microbial …, 2023 - Elsevier
Neisseria gonorrhoeae (Ngo) has emerged as a global threat leading to one of the most
common sexually transmitted diseases in the world. It has also become one of the leading …