There are multiple reasons why the next generation of biological and medical studies
require increasing numbers of samples. Biological systems are dynamic, and the effect of a …

Our understanding of the molecular mechanisms underlying cancer development and
evolution have evolved rapidly over recent years, and the variation from one patient to …

Chimeric antigen receptor (CAR)-modified natural killer (NK) cells show antileukemic activity
against acute myeloid leukemia (AML) in vivo. However, NK cell-mediated tumor killing is …

Deep single-cell multi-omic profiling offers a promising approach to understand and
overcome drug resistance in relapsed or refractory (rr) acute myeloid leukemia (AML). Here …

Multiple myeloma (MM) is a plasma cell malignancy of the bone marrow. Despite therapeutic
advances, MM remains incurable, and better risk stratification as well as new therapies are …

Mitochondrial metabolism recently emerged as a critical dependency in acute myeloid
leukemia (AML). The shape of mitochondria is tightly regulated by dynamin GTPase …

Mass spectrometry‐based phosphoproteomics has identified> 150,000 post‐translational
phosphorylation sites in the human proteome. To disentangle their functional relevance …

Mass spectrometry-based proteomics plays a critical role in current biological and clinical
research. Technical issues like data integration, missing value imputation, batch effect …

Classifications of acute myeloid leukemia (AML) patients rely on morphologic, cytogenetic,
and molecular features. Here we have established a novel flow cytometry-based …

During the last decades, remarkable progress has been made in further understanding the
complex molecular regulatory networks that maintain hematopoietic stem cell (HSC) …