Plant-derived exosomes (PDEs) are natural extracellular vesicles (EVs). In the current
decade, they have been highlighted for cancer therapeutic development. Cancer is a global …

Accumulating evidence indicates an alarming increase in the incidence of early-onset
cancers, which are diagnosed among adults under 50 years of age, in the colorectum …

We report that~ 1.8% of all mesothelioma patients and 4.9% of those younger than 55, carry
rare germline variants of the BRCA1 associated RING domain 1 (BARD1) gene that were …

Conjugated linoleic acid (CLA) has been extensively characterized due to its many
biological activities and health benefits, but conjugated linolenic acid (CLnA) is still not well …

Objective To examine and interpret trends in UK cancer incidence and mortality for all
cancers combined and for the most common cancer sites in adults aged 35-69 years …

Background Accurate and up-to-date estimates of the global cancer burden in adolescents
and young adults (AYA) are scarce. This study aims to assess the global burden and trends …

Endothelin-1 (ET-1) plays a physiological role as a potent vasoconstrictor. It is implicated in
an array of diseases, and its signalling is often found to be overactivated within cancers. ET …

Background The rising burden of thyroid cancer (TC) is a public health problem in Asia.
Predicting the future burden of TC in Asian countries is essential for disease prevention …

The global burden of cancer incidence, deaths and economic costs is steadily increasing
since several decades. Despite a massive allocation of research funds since the 1970s, no …

The incidence of early-onset cancers in adolescents and young adults (AYA) has been
increasing worldwide since the 1990s. In Italy, a significant increased rate of 1.6% per year …