Pituitary adenylate cyclase‐activating peptide in the rat central nervous system: an immunohistochemical and in situ hybridization study
J Hannibal - Journal of Comparative Neurology, 2002 - Wiley Online Library
In the present study the localization of pituitary adenylate cyclase‐activating peptide
(PACAP)‐expressing cell bodies and PACAP projections were mapped in the adult rat brain …
(PACAP)‐expressing cell bodies and PACAP projections were mapped in the adult rat brain …
Current state of understanding of the role of PACAP in the hypothalamo-hypophyseal gonadotropin functions of mammals
K Köves, E Szabó, O Kántor, A Heinzlmann… - Frontiers in …, 2020 - frontiersin.org
PACAP was discovered 30 years ago in Dr. Akira Arimura's laboratory. In the past three
decades since then, it has become evident that this peptide plays numerous crucial roles in …
decades since then, it has become evident that this peptide plays numerous crucial roles in …
PACAP: A regulator of mammalian reproductive function
SJ Winters, JP Moore Jr - Molecular and cellular endocrinology, 2020 - Elsevier
Pituitary adenylate cyclase-activating polypeptide (PACAP) is an ancestral molecule that
was isolated from sheep hypothalamic extracts based on its action to stimulate cAMP …
was isolated from sheep hypothalamic extracts based on its action to stimulate cAMP …
PACAP modulates GnRH signaling in gonadotropes
LM Halvorson - Molecular and cellular endocrinology, 2014 - Elsevier
Hypothalamic gonadotropin-releasing hormone is known to be critical for normal
gonadotropin biosynthesis and secretion by the gonadotrope cells of the anterior pituitary …
gonadotropin biosynthesis and secretion by the gonadotrope cells of the anterior pituitary …
History of the Development of Knowledge about the Neuroendocrine Control of Ovulation—Recent Knowledge on the Molecular Background
F Szabó, K Köves, L Gál - International Journal of Molecular Sciences, 2024 - mdpi.com
The physiology of reproduction has been of interest to researchers for centuries. The
purpose of this work is to review the development of our knowledge on the neuroendocrine …
purpose of this work is to review the development of our knowledge on the neuroendocrine …
The role of PACAP in gonadotropic hormone secretion at hypothalamic and pituitary levels
K Köves, O Kántor, J Molnár, A Heinzlmann… - Journal of Molecular …, 2003 - Springer
The presence of pituitary adenylate cyclase-activating polypeptide (PACAP) and its mRNA
in the three levels of the hypothalamo-hypophyseal-ovarian axis was previously …
in the three levels of the hypothalamo-hypophyseal-ovarian axis was previously …
Neonatal PACAP administration in rats delays puberty through the influence of the LHRH neuronal system
F Szabo, J Horvath, A Heinzlmann, A Arimura… - Regulatory peptides, 2002 - Elsevier
The onset of puberty is a concerted action of many factors which leads to cyclic LHRH
release in rats. It has been demonstrated that; in common with vasoactive intestinal …
release in rats. It has been demonstrated that; in common with vasoactive intestinal …
Advent and recent advances in research on the role of pituitary adenylate cyclase-activating polypeptide (PACAP) in the regulation of gonadotropic hormone secretion …
PACAP (ADCYAP1) was isolated from ovine hypothalami. PACAP activates three distinct
receptor types: G-protein coupled PAC1, VPAC1, and VPAC2 with seven transmembrane …
receptor types: G-protein coupled PAC1, VPAC1, and VPAC2 with seven transmembrane …
Cell immunoblot assay study demonstrating the release of PACAP from individual anterior pituitary cells of rats and the effect of PACAP on LH release
E Szabo, A Nemeskeri, A Heinzlmann, N Suzuki… - Regulatory peptides, 2002 - Elsevier
The presence of pituitary adenylate cyclase activating polypeptide (PACAP) was previously
demonstrated in the anterior pituitary by radioimmunoassay, immunohistochemistry, and …
demonstrated in the anterior pituitary by radioimmunoassay, immunohistochemistry, and …
Pituitary adenylate cyclase–activating polypeptide (PACAP) in the hypothalamic–pituitary–gonadal axis: A review of the literature
RL Thomas, NM Crawford, CM Grafer… - Reproductive …, 2013 - journals.sagepub.com
Pituitary adenylate cyclase–activating polypeptide (PACAP), an ancient molecule highly
preserved across species, has been classified as a member of the secretin/glucagon …
preserved across species, has been classified as a member of the secretin/glucagon …