In theory, in vitro and in vivo models for human gliomas have great potential to not only
enhance our understanding of glioma biology, but also to facilitate the development of novel …

Zebrafish (Danio rerio) is an ideal in vivo model to study a wide variety of human cancer
types. In this review, we provide a comprehensive overview of zebrafish in the cancer drug …

As a promising in vivo tool for cancer research, zebrafish have been widely applied in
various tumor studies. The zebrafish xenograft model is a low-cost, high-throughput tool for …

The use of patient-derived primary cell cultures in cancer preclinical assays has increased in
recent years. The management of resected tumor tissue remains complex and a number of …

Flavonoids are well-known antioxidants and have shown the ability to prevent tumor
formation and recurrence. Especially in dietary flavonoids, they have provided convenience …

In an era of high-throughput “omic” technologies, the unprecedented amount of data that can
be generated presents a significant opportunity but simultaneously an even greater …

Head and neck cancers (HNCs) represent the sixth most widespread malignancy worldwide.
Surgery, radiotherapy, chemotherapeutic and immunotherapeutic drugs represent the main …

The first steps towards establishing xenografts in zebrafish embryos were performed by Lee
et al., 2005 and Haldi et al., 2006, paving the way for studying human cancers using this …

Cancer therapeutics currently have the lowest clinical trial success rate of all major
diseases. Partly as a result of the paucity of successful anti-cancer drugs, cancer will soon …

Increasing accumulation and retention of nanomedicines within tumor tissue is a significant
challenge, particularly in the case of brain tumors where access to the tumor through the …