Mechanical Loading Modulates AMPK and mTOR Signaling in Muscle Cells

X Zhou, S Zhu, J Li, A Mateus, C Williams… - Journal of Proteome …, 2024 - ACS Publications
Skeletal muscle adaptation to exercise involves various phenotypic changes that enhance
the metabolic and contractile functions. One key regulator of these adaptive responses is the …

Effect of tetrahedral framework nucleic acids on the reconstruction of tendon‐to‐bone injuries after rotator cuff tears

P Li, L Fu, C Ning, J Wu, Z Xu, Z Liao, C Gao… - Cell …, 2024 - Wiley Online Library
Clinicians and researchers have always faced challenges in performing surgery for rotator
cuff tears (RCT) due to the intricate nature of the tendon‐bone gradient and the limited long …

Secretome from myoblasts statically loaded at low intensity promotes tenocyte proliferation via the IGF-1 receptor pathway

J Li, X Zhou, J Chen, P Eliasson, PJ Kingham… - The FASEB …, 2023 - diva-portal.org
Exercise is widely recognized as beneficial for tendon healing. Recently, it has been
described that muscle-derived molecules secreted in response to static exercise influence …

Effects of Late-Passage Small Umbilical Cord–Derived Fast Proliferating Cells on Tenocytes from Degenerative Rotator Cuff Tears under an Interleukin 1β-Induced …

AY Lee, JY Park, SJ Hwang, KH Jang… - Tissue Engineering and …, 2024 - Springer
Background Tendinopathy is a chronic tendon disease. Mesenchymal stem cells (MSCs),
known for their anti-inflammatory properties, may lose effectiveness with extensive culturing …

Healing of Ligaments and Tendons: Tissue Engineering and Models

GG Schulze-Tanzil - International Journal of Molecular Sciences, 2022 - mdpi.com
The aim of this Special Issue is to summarize the latest developments in tendon/ligament
research and tissue engineering (TE), providing helpful approaches for future …

Influences of Tensile Forces and Nanofiber Alignment on Innervated and Non-Innervated Skeletal Myocyte Maturation in Custom Mechanobioreactors

MC Hilman, F Mourkioti, S Das… - ESS Open Archive eprints, 2024 - authorea.com
While it is well understood that muscle tissue generates contractile forces, it is less
appreciated that muscle also dynamically responds to applied forces during development as …

Mesenchymal Stem Cell Secretome Effectiveness on Healing of Chronic Tendon Injury: Analysis of Procollagen Type I N-Terminal Peptide and Procollagen Type Iii N …

ADP Sam, W Warsinggih, MA Usman, MP Johan… - 2024 - researchsquare.com
Background Chronic tendon injuries, such as Achilles tendinopathy, are common and
challenging to treat due to the limited regenerative capacity of tendon tissue. Using …