Virulence is described as an ability of an organism to infect the host and cause a disease.
Virulence factors are the molecules that assist the bacterium colonize the host at the cellular …

L-serine is a nonessential amino acid in eukaryotic cells, used for protein synthesis and in
producing phosphoglycerides, glycerides, sphingolipids, phosphatidylserine, and …

Background Despite the various strategies undertaken in the clinical practice, the mortality
rate due to antibiotic-resistant microbes has been markedly increasing worldwide. In …

Colorectal cancer (CRC) is one of the main causes of cancer-related deaths worldwide.
Sporadic CRC develops from normal mucosa via adenoma to adenocarcinoma, which …

Tuberculosis caused by the bacterium, Mycobacterium tuberculosis (Mtb), continues to
remain one of the most devastating infectious diseases afflicting humans. Although there are …

Covering: up to June, 2020 Tuberculosis (TB) continues to be a major disease with high
mortality and morbidity globally. Drug resistance and long duration of treatment make …

Advances in sequencing technologies have led to a rapid growth of public protein sequence
databases, whereby the fraction of proteins with experimentally verified function …

The granuloma is the hallmark of tuberculosis and simultaneously signifies acquisition of an
infection and induction of a host immune response. But who benefits more from the …

Tuberculosis is currently still one of the leading causes of death from a treatable pathogen.
The proportion of cases of resistance to common antibiotics is frequently increasing and the …

Inorganic polyphosphate (PolyP) plays an essential role in microbial stress adaptation,
virulence and drug tolerance. The genome of Mycobacterium tuberculosis encodes for two …