Peroxisomal fatty acid degradation in the yeast Saccharomyces cerevisiae requires an array
of β-oxidation enzyme activities as well as a set of auxiliary activities to provide the β …

The benzoquinone ubiquinone (coenzyme Q) and the naphthoquinones menaquinone
(vitamin K 2) and demethylmenaquinone are derived from the shikimate pathway, which has …

A gene encoding a novel enoyl-SCoA hydratase/lyase enzyme for the hydration and
nonoxidative cleavage of feruloyl-SCoA to vanillin and acetyl-SCoA was isolated and …

We have determined the crystal structure of the enzyme enoyl-CoA hydratase (ECH) from rat
liver with the bound substrate 4-(N, N-dimethylamino) cinnamoyl-CoA using X-ray diffraction …

Bacterial enzymes of the menaquinone (Vitamin K 2) pathway are potential drug targets
because they lack human homologs. MenB, 1, 4-dihydroxy-2-naphthoyl-CoA synthase, the …

This review presents the synthesis of coenzyme A (CoA), its esters, and analogues and the
application of these compounds in studies of CoA ester-utilizing enzymes. The primary focus …

Escherichia coli and Salmonella contain the naphthoquinones menaquinone (MK; vitamin
K2) and demethylmenaquinone and the benzoquinone ubiquinone (coenzyme Q; Q). Both …

The structure of the hexameric rat mitochondrial enoyl-Coenzyme A (CoA) hydratase, co-
crystallised with the inhibitor octanoyl-CoA, has been refined at a resolution of 2.4 Å. Enoyl …

MenB, the 1, 4-dihydroxy-2-naphthoyl-CoA synthase from the bacterial menaquinone
biosynthesis pathway, catalyzes an intramolecular Claisen condensation (Dieckmann …

The (R)-specific enoyl coenzyme A hydratase ((R)-hydratase) from Aeromonas caviae
catalyzes the addition of a water molecule totrans-2-enoyl coenzyme A (CoA), with a chain …