An updated review summarizing the anticancer efficacy of melittin from bee venom in several models of human cancers

P Pandey, F Khan, MA Khan, R Kumar, TK Upadhyay - Nutrients, 2023 - mdpi.com
Apitherapy (using bee products) has gained broad recognition in cancer therapeutics
globally. Honeybee venom has a broad range of biological potential, and its utilization is …

Can bee venom be used as anticancer agent in modern medicine?

A Małek, M Strzemski, J Kurzepa, J Kurzepa - Cancers, 2023 - mdpi.com
Simple Summary The beneficial effects of natural substances that have been used in
medicine for many years require both scientific confirmation and recognition of the …

Harnessing the power of bee venom for therapeutic and regenerative medical applications: an updated review

KM Sadek, NA Shib, ES Taher, F Rashed… - Frontiers in …, 2024 - frontiersin.org
Honeybees have been helpful insects since ancient centuries, and this benefit is not limited
to being a honey producer only. After the bee stings a person, pain, and swelling occur in …

The current landscape of the antimicrobial peptide melittin and its therapeutic potential

HQ Zhang, C Sun, N Xu, W Liu - Frontiers in Immunology, 2024 - frontiersin.org
Melittin, a main component of bee venom, is a cationic amphiphilic peptide with a linear α-
helix structure. It has been reported that melittin can exert pharmacological effects, such as …

Chemical composition and antimicrobial properties of honey bee venom

V Isidorov, A Zalewski, G Zambrowski, I Swiecicka - Molecules, 2023 - mdpi.com
Due to its great medical and pharmaceutical importance, honey bee venom is considered to
be well characterized both chemically and in terms of biomedical activity. However, this …

[HTML][HTML] Melittin and phospholipase A2: Promising anti-cancer candidates from bee venom

Z Cui, Z Zhou, Z Sun, J Duan, R Liu, C Qi… - Biomedicine & …, 2024 - Elsevier
As the research on cancer-related treatment deepens, integrating traditional therapies with
emerging interventions reveals new therapeutic possibilities. Melittin and phospholipase A2 …

[HTML][HTML] Venom Ex Machina? Exploring the Potential of Cell-Free Protein Production for Venom Biodiscovery

A Paas, J Dresler, L Talmann, A Vilcinskas… - International Journal of …, 2024 - mdpi.com
Venoms are a complex cocktail of potent biomolecules and are present in many animal
lineages. Owed to their translational potential in biomedicine, agriculture and industrial …

Prevalent bee venom genes evolved before the aculeate stinger and eusociality

I Koludarov, M Velasque, T Senoner, T Timm, C Greve… - BMC biology, 2023 - Springer
Background Venoms, which have evolved numerous times in animals, are ideal models of
convergent trait evolution. However, detailed genomic studies of toxin-encoding genes exist …

Identification of Protein Quality Markers in Toad Venom from Bufo gargarizans

M Yang, W Huan, G Zhang, J Li, F Xia, R Durrani… - Molecules, 2023 - mdpi.com
Toad venom is a traditional Chinese medicine with high medicinal value. The existing
quality evaluation standards of toad venom have obvious limitations because of the lack of …

Dimerization and lysine substitution of melittin have differing effects on bacteria

T Matthyssen, W Li, JA Holden, JC Lenzo… - Frontiers in …, 2024 - frontiersin.org
Introduction Melittin is a potent antimicrobial peptide from bee venom that is effective against
both Gram-positive and Gram-negative bacteria. However, it is extremely toxic to …