Membrane proteins play a most important part in metabolism, signaling, cell motility,
transport, development, and many other biochemical and biophysical processes which …

Atomic-resolution structural studies of membrane-associated proteins and peptides in a
membrane environment are important to fully understand their biological function and the …

Membrane proteins usually need to be extracted from their native environment and
separated from other membrane components for in-depth in vitro characterization. The use …

New technologies for the purification of stable membrane proteins have emerged in recent
years, in particular methods that allow the preparation of membrane proteins with their …

Biological characterisation of membrane proteins lags behind that of soluble proteins. This
reflects issues with the traditional use of detergents for extraction, as the surrounding lipids …

Solubilisation of biological lipid bilayer membranes for analysis of their protein complement
has traditionally been carried out using detergents, but there is increasing interest in the use …

Of the four separate PE biosynthetic pathways in eukaryotes, one occurs in the
mitochondrial inner membrane (IM) and is executed by phosphatidylserine decarboxylase …

Some styrene/maleic acid (SMA) copolymers solubilise membrane lipids and proteins to
form polymer-bounded nanodiscs termed SMA/lipid particles (SMALPs). Although SMALPs …

Amphipathic styrene-maleic acid (SMA) copolymers directly solubilize biomembranes into
SMA-lipid particles, or SMALPs, that are often regarded as nanodiscs and hailed as a native …

Membrane proteins (MPs) are the gatekeepers between different biological compartments
separated by lipid bilayers. Being receptors, channels, transporters, or primary pumps, they …