Dynamic switching of crotonylation to ubiquitination of H2A at lysine 119 attenuates transcription–replication conflicts caused by replication stress
S Hao, Y Wang, Y Zhao, W Gao, W Cui… - Nucleic Acids …, 2022 - academic.oup.com
The reversible post-translational modification (PTM) of proteins plays an important role in
many cellular processes. Lysine crotonylation (Kcr) is a newly identified PTM, but its …
many cellular processes. Lysine crotonylation (Kcr) is a newly identified PTM, but its …
Kelch-like proteins in the gastrointestinal tumors
A Fu, S Xiang, Q He, M Ying - Acta Pharmacologica Sinica, 2023 - nature.com
Gastrointestinal tumors have become a worldwide health problem with high morbidity and
poor clinical outcomes. Chemotherapy and surgery, the main treatment methods, are still far …
poor clinical outcomes. Chemotherapy and surgery, the main treatment methods, are still far …
Small ORFs as New Regulators of Pri-miRNAs and miRNAs Expression in Human and Drosophila
C Dozier, A Montigny, M Viladrich, R Culerrier… - International Journal of …, 2022 - mdpi.com
MicroRNAs (miRNAs) are small regulatory non-coding RNAs, resulting from the cleavage of
long primary transcripts (pri-miRNAs) in the nucleus by the Microprocessor complex …
long primary transcripts (pri-miRNAs) in the nucleus by the Microprocessor complex …
A novel RBBP8 (p. E281*) germline mutation is a predisposing mutation in familial hereditary cancer syndrome
J Yan, J Wu, Y Wang, X Di, H Jiang, D Wen, D Li… - Journal of Molecular …, 2023 - Springer
Screening tumor susceptibility genes helps in identifying powerful biomarkers for hereditary
cancer monitoring, prevention, and diagnosis, providing opportunities for understanding …
cancer monitoring, prevention, and diagnosis, providing opportunities for understanding …
[HTML][HTML] The CtIP-CtBP1/2-HDAC1-AP1 transcriptional complex is required for the transrepression of DNA damage modulators in the pathogenesis of osteosarcoma
X Chen, Q Zhang, X Dang, J Fan, T Song, Z Li… - Translational …, 2022 - Elsevier
Most tumors, including osteosarcomas, have deficiencies in DNA damage repair. However,
the regulatory mechanisms underlying dysregulation of DNA damage repair genes are still …
the regulatory mechanisms underlying dysregulation of DNA damage repair genes are still …
[PDF][PDF] A novel RBBP8 (c. 841G> T) germline mutation is a predisposition mutation in familial hereditary cancer syndrome
J Yan, J Wu, Y Wang, X Di, H Jiang, D Wen, S Zhang - 2023 - scholar.archive.org
Background: Screening tumor susceptibility genes will be found powerful biomarkers for
hereditary cancer monitoring, prevention and diagnosis, which providing opportunities for …
hereditary cancer monitoring, prevention and diagnosis, which providing opportunities for …