The human gastrointestinal tract is populated with a diverse microbial community. The vast
genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every …

Oligodendrocytes are best known for wrapping myelin, a unique specialization that enables
energy-efficient and fast axonal impulse propagation in white matter tracts and fibers of the …

Alzheimer's disease (AD) is the leading cause of dementia in older adults. Although AD
progression is characterized by stereotyped accumulation of proteinopathies, the affected …

Amyloid-β (Aβ) is thought to be neuronally derived in Alzheimer's disease (AD). However,
transcripts of amyloid precursor protein (APP) and amyloidogenic enzymes are equally …

Age-related myelin damage induces inflammatory responses, yet its involvement in
Alzheimer's disease remains uncertain, despite age being a major risk factor. Using a …

Alzheimer´ s disease (AD) stands out as the most common chronic neurodegenerative
disorder. AD is characterized by progressive cognitive decline and memory loss, with …

Reduction of amyloid beta (Aβ) has been shown to be effective in treating Alzheimer's
disease (AD), but the underlying assumption that neurons are the main source of pathogenic …

Optic nerve disorders encompass a wide spectrum of conditions characterized by the loss of
retinal ganglion cells (RGCs) and subsequent degeneration of the optic nerve. The etiology …

Alzheimer's disease (AD) is the most common neurodegenerative disorder, characterized
pathologically by extracellular deposition of β-amyloid (Aβ) into senile plaques and …

Dynamically organized chromatin complexes often involve multiplex chromatin interactions
and sometimes chromatin-associated RNA,–. Chromatin complex compositions change …