Polyaromatic hydrocarbons in pollution: a heart‐breaking matter

CR Marris, SN Kompella, MR Miller… - The Journal of …, 2020 - Wiley Online Library
Air pollution is associated with detrimental effects on human health, including decreased
cardiovascular function. However, the causative mechanisms behind these effects have yet …

Zebrafish heart failure models

S Narumanchi, H Wang, S Perttunen… - Frontiers in cell and …, 2021 - frontiersin.org
Heart failure causes significant morbidity and mortality worldwide. The understanding of
heart failure pathomechanisms and options for treatment remain incomplete. Zebrafish has …

Arrhythmic Effects Evaluated on Caenorhabditis elegans: The Case of Polypyrrole Nanoparticles

SY Srinivasan, PA Illera, D Kukhtar… - ACS …, 2023 - ACS Publications
Experimental studies and clinical trials of nanoparticles for treating diseases are increasing
continuously. However, the reach to the market does not correlate with these efforts due to …

The zebrafish heart as a model of mammalian cardiac function

CE Genge, E Lin, L Lee, XY Sheng, K Rayani… - Reviews of Physiology …, 2016 - Springer
Zebrafish (Danio rerio) are widely used as vertebrate model in developmental genetics and
functional genomics as well as in cardiac structure-function studies. The zebrafish heart has …

The sarcoplasmic reticulum and the evolution of the vertebrate heart

HA Shiels, GLJ Galli - Physiology, 2014 - journals.physiology.org
The sarcoplasmic reticulum (SR) is crucial for contraction and relaxation of the mammalian
cardiomyocyte, but its role in other vertebrate classes is equivocal. Recent evidence …

Modeling human cardiac arrhythmias: insights from zebrafish

S Gauvrit, J Bossaer, J Lee, MM Collins - Journal of Cardiovascular …, 2022 - mdpi.com
Cardiac arrhythmia, or irregular heart rhythm, is associated with morbidity and mortality and
is described as one of the most important future public health challenges. Therefore …

Forward genetic screen using a gene-breaking trap approach identifies a novel role of grin2bb-associated RNA transcript (grin2bbART) in zebrafish heart function

RS Angom, A Joshi, A Patowary, A Sivadas… - Frontiers in Cell and …, 2024 - frontiersin.org
LncRNA-based control affects cardiac pathophysiologies like myocardial infarction, coronary
artery disease, hypertrophy, and myotonic muscular dystrophy. This study used a gene …

Zebrafish as a model of cardiac pathology and toxicity: spotlight on uremic toxins

A Coppola, P Lombari, E Mazzella… - International Journal of …, 2023 - mdpi.com
Chronic kidney disease (CKD) is an increasing health care problem. About 10% of the
general population is affected by CKD, representing the sixth cause of death in the world …

Electrical excitability of the fish heart and its autonomic regulation

M Vornanen - Fish physiology, 2017 - Elsevier
A key factor determining the pumping function of the fish heart is the regulation of electrical
excitability of cardiac myocytes in the pacemaker region, the atrium and the ventricle …

Agrochemical-mediated cardiotoxicity in zebrafish embryos/larvae: What we do and where we go

Y Yang, Y Tao, Z Li, Y Cui, J Zhang… - Critical Reviews in …, 2023 - Taylor & Francis
The massive application of agrochemicals and associated environmental residues greatly
threaten human health. Cardiac dysfunction, as a major contributing factor to human …