The role of miRNAs in ovarian cancer pathogenesis and therapeutic resistance–a focus on signaling pathways interplay

A Ismail, AI Abulsoud, D Fathi, A Elshafei… - … -Research and Practice, 2022 - Elsevier
One of the most prevalent and lethal forms of gynecological cancer is ovarian cancer (OC),
which is often diagnosed in its latter, deadly stages. The OC's high mortality and …

MicroRNAome genome: a treasure for cancer diagnosis and therapy

I Berindan‐Neagoe, PC Monroig… - CA: a cancer journal …, 2014 - Wiley Online Library
The interplay between abnormalities in genes coding for proteins and noncoding
microRNAs (miRNAs) has been among the most exciting yet unexpected discoveries in …

Integrated extracellular microRNA profiling for ovarian cancer screening

A Yokoi, J Matsuzaki, Y Yamamoto, Y Yoneoka… - Nature …, 2018 - nature.com
A major obstacle to improving prognoses in ovarian cancer is the lack of effective screening
methods for early detection. Circulating microRNAs (miRNAs) have been recognized as …

Let-7 as biomarker, prognostic indicator, and therapy for precision medicine in cancer

E Chirshev, KC Oberg, YJ Ioffe… - Clinical and translational …, 2019 - Springer
Abnormal regulation and expression of microRNAs (miRNAs) has been documented in
various diseases including cancer. The miRNA let-7 (MIRLET7) family controls …

MicroRNAs as potential biomarkers in cancer: opportunities and challenges

H Lan, H Lu, X Wang, H Jin - BioMed research international, 2015 - Wiley Online Library
MicroRNAs (miRNAs) are a group of small noncoding RNAs (ncRNAs) that
posttranscriptionally regulate gene expression by targeting their corresponding messenger …

Circulating miRNAs: roles in cancer diagnosis, prognosis and therapy

G Cheng - Advanced drug delivery reviews, 2015 - Elsevier
MicroRNAs (miRNAs) belong to a class of small non-coding RNAs that regulate numerous
biological processes by targeting a broad set of messenger RNAs. Recently, miRNAs have …

New concepts in cancer biomarkers: circulating miRNAs in liquid biopsies

E Larrea, C Sole, L Manterola, I Goicoechea… - International journal of …, 2016 - mdpi.com
The effective and efficient management of cancer patients relies upon early diagnosis and/or
the monitoring of treatment, something that is often difficult to achieve using standard tissue …

miRNAs and ovarian cancer: An overview

B Deb, A Uddin, S Chakraborty - Journal of cellular physiology, 2018 - Wiley Online Library
Ovarian cancer (OC) is the sixth most common cancer in women globally. However, even
with the advances in detection and therapeutics it still represents the most dangerous …

Clinical relevance of circulating cell-free microRNAs in ovarian cancer

K Nakamura, K Sawada, A Yoshimura, Y Kinose… - Molecular cancer, 2016 - Springer
Ovarian cancer is the leading cause of death among gynecologic malignancies. Since
ovarian cancer develops asymptomatically, it is often diagnosed at an advanced and …

Liquid biopsy in ovarian cancer: the potential of circulating miRNAs and exosomes

L Giannopoulou, M Zavridou, S Kasimir-Bauer… - Translational …, 2019 - Elsevier
Ovarian cancer still remains the most lethal female cancer, since in most cases it is
diagnosed at an advanced stage. Usually after completion of primary treatment …