A complete understanding of DNA double-helical structure discovered by James Watson
and Francis Crick in 1953, unveil the importance and significance of DNA. For the last seven …

Deficiency of hypoxanthine-guanine phosphoribosyltransferase (HPRT) activity is an inborn
error of purine metabolism associated with uric acid overproduction and a continuum …

Updated to reflect the newest changes in genetics, Thompson & Thompson's Genetics in
Medicine returns as one of the most favored texts in this fascinating and rapidly evolving …

Tandemly reiterated sequences represent a rich source of highly polymorphic markers for
genetic linkage, mapping, and personal identification. Human trimeric and tetrameric short …

Synthetic oligonucleotides containing GC-rich triplet sequences were used in a scanning
strategy to identify unstable genetic sequences at the myotonic dystrophy (DM) locus. A …

Preparation and application of new monosized polymer particles - ScienceDirect Skip to
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We have used two new dye sets for automated dye-labeled terminator DNA sequencing.
One set consists of four, 4, 7-dichlororhodamine dyes (d-rhodamines). The second set …

Array comparative genomic hybridization (aCGH) is a powerful tool for the molecular
elucidation and diagnosis of disorders resulting from genomic copy‐number variation …

Recent studies have revealed that tumors in patients with hereditary nonpolyposis colon
cancer are associated with high-frequency alterations of microsatellite sequences. To …

Epidermolytic hyperkeratosis is a hereditary skin disorder characterized by blistering and a
marked thickening of the stratum corneum. In one family, affected individuals exhibited a …