[HTML][HTML] Monoclonal antibodies in cancer therapy

D Zahavi, L Weiner - Antibodies, 2020 - mdpi.com
Monoclonal antibody-based immunotherapy is now considered to be a main component of
cancer therapy, alongside surgery, radiation, and chemotherapy. Monoclonal antibodies …

Recent advances in hyperthermia therapy‐based synergistic immunotherapy

M Chang, Z Hou, M Wang, C Li, J Lin - Advanced Materials, 2021 - Wiley Online Library
The past decades have witnessed hyperthermia therapy (HTT) as an emerging strategy
against malignant tumors. Nanomaterial‐based photothermal therapy (PTT) and magnetic …

Efficacy and safety of nivolumab plus ipilimumab in patients with advanced hepatocellular carcinoma previously treated with sorafenib: the CheckMate 040 …

T Yau, YK Kang, TY Kim, AB El-Khoueiry… - JAMA …, 2020 - jamanetwork.com
Importance Most patients with hepatocellular carcinoma (HCC) are diagnosed with
advanced disease not eligible for potentially curative therapies; therefore, new treatment …

Reactive oxygen species (ROS)-based nanomedicine

B Yang, Y Chen, J Shi - Chemical reviews, 2019 - ACS Publications
Reactive oxygen species (ROS) play an essential role in regulating various physiological
functions of living organisms. The intrinsic biochemical properties of ROS, which underlie …

Enhancing anti-tumour efficacy with immunotherapy combinations

F Meric-Bernstam, J Larkin, J Tabernero, C Bonini - The Lancet, 2021 - thelancet.com
Several tumour types are responsive to immunotherapy, as shown by regulatory approvals
for immune checkpoint inhibitors. However, many patients either do not respond or do not …

[HTML][HTML] Cytokines in clinical cancer immunotherapy

P Berraondo, MF Sanmamed, MC Ochoa… - British journal of …, 2019 - nature.com
Cytokines are soluble proteins that mediate cell-to-cell communication. Based on the
discovery of the potent anti-tumour activities of several pro-inflammatory cytokines in animal …

[HTML][HTML] A paradigm shift in cancer immunotherapy: from enhancement to normalization

MF Sanmamed, L Chen - Cell, 2018 - cell.com
Harnessing an antitumor immune response has been a fundamental strategy in cancer
immunotherapy. For over a century, efforts have primarily focused on amplifying immune …

Nanocatalytic medicine

B Yang, Y Chen, J Shi - Advanced materials, 2019 - Wiley Online Library
Catalysis and medicine are often considered as two independent research fields with their
own respective scientific phenomena. Promoted by recent advances in nanochemistry, large …

Neoadjuvant nivolumab modifies the tumor immune microenvironment in resectable glioblastoma

KA Schalper, ME Rodriguez-Ruiz, R Diez-Valle… - Nature medicine, 2019 - nature.com
Glioblastoma is the most common primary central nervous system malignancy and has a
poor prognosis. Standard first-line treatment, which includes surgery followed by adjuvant …

First-line pembrolizumab and trastuzumab in HER2-positive oesophageal, gastric, or gastro-oesophageal junction cancer: an open-label, single-arm, phase 2 trial

YY Janjigian, SB Maron, WK Chatila, B Millang… - The Lancet …, 2020 - thelancet.com
Background Addition of trastuzumab to first-line chemotherapy improves overall survival in
patients with HER2-positive metastatic gastric cancer. We assessed the safety and activity of …