Gene regulatory network inference in the era of single-cell multi-omics
P Badia-i-Mompel, L Wessels, S Müller-Dott… - Nature Reviews …, 2023 - nature.com
The interplay between chromatin, transcription factors and genes generates complex
regulatory circuits that can be represented as gene regulatory networks (GRNs). The study …
regulatory circuits that can be represented as gene regulatory networks (GRNs). The study …
Overview of microRNA biogenesis, mechanisms of actions, and circulation
MicroRNAs (miRNAs) are a class of non-coding RNAs that play important roles in regulating
gene expression. The majority of miRNAs are transcribed from DNA sequences into primary …
gene expression. The majority of miRNAs are transcribed from DNA sequences into primary …
miRNet 2.0: network-based visual analytics for miRNA functional analysis and systems biology
Abstract miRNet is an easy-to-use, web-based platform designed to help elucidate
microRNA (miRNA) functions by integrating users' data with existing knowledge via network …
microRNA (miRNA) functions by integrating users' data with existing knowledge via network …
Regulatory network of miRNA on its target: coordination between transcriptional and post-transcriptional regulation of gene expression
MicroRNAs (miRNAs) are a class of endogenous small noncoding RNAs that participate in a
majority of biological processes via regulating target gene expression. The post …
majority of biological processes via regulating target gene expression. The post …
A network-biology perspective of microRNA function and dysfunction in cancer
MicroRNAs (miRNAs) participate in most aspects of cellular differentiation and homeostasis,
and consequently have roles in many pathologies, including cancer. These small non …
and consequently have roles in many pathologies, including cancer. These small non …
MicroRNA and transcription factor: key players in plant regulatory network
AFA Samad, M Sajad, N Nazaruddin, IA Fauzi… - Frontiers in plant …, 2017 - frontiersin.org
Recent achievements in plant microRNA (miRNA), a large class of small and non-coding
RNAs, are very exciting. A wide array of techniques involving forward genetic, molecular …
RNAs, are very exciting. A wide array of techniques involving forward genetic, molecular …
[HTML][HTML] Network resilience
Many systems on our planet shift abruptly and irreversibly from the desired state to an
undesired state when forced across a “tipping point”. Some examples are mass extinctions …
undesired state when forced across a “tipping point”. Some examples are mass extinctions …
Systems biology-based investigation of cooperating microRNAs as monotherapy or adjuvant therapy in cancer
MicroRNAs (miRNAs) are short, noncoding RNAs that regulate gene expression by
suppressing mRNA translation and reducing mRNA stability. A miRNA can potentially bind …
suppressing mRNA translation and reducing mRNA stability. A miRNA can potentially bind …
MicroRNAs as regulators of insulin signaling: research updates and potential therapeutic perspectives in type 2 diabetes
L Nigi, GE Grieco, G Ventriglia, N Brusco… - International journal of …, 2018 - mdpi.com
The insulin signaling pathway is composed of a large number of molecules that positively or
negatively modulate insulin specific signal transduction following its binding to the cognate …
negatively modulate insulin specific signal transduction following its binding to the cognate …
[图书][B] A first course in systems biology
E Voit - 2017 - taylorfrancis.com
A First Course in Systems Biology is an introduction for advanced undergraduate and
graduate students to the growing field of systems biology. Its main focus is the development …
graduate students to the growing field of systems biology. Its main focus is the development …