Oxidative stress and natural antioxidants in osteoporosis: Novel preventive and therapeutic approaches

G Marcucci, V Domazetovic, C Nediani, J Ruzzolini… - Antioxidants, 2023 - mdpi.com
This review reports in detail the cellular and molecular mechanisms which regulate the bone
remodeling process in relation to oxidative stress (OS), inflammatory factors, and estrogen …

Polyphenols targeting MAPK mediated oxidative stress and inflammation in rheumatoid arthritis

T Behl, T Upadhyay, S Singh, S Chigurupati… - Molecules, 2021 - mdpi.com
Rheumatoid arthritis (RA) is a chronic, systemic, autoimmune disorder, predominantly
symmetric, which causes joint inflammation, cartilage degeneration and bone erosion …

The anti-inflammatory properties of phytochemicals and their effects on epigenetic mechanisms involved in TLR4/NF-κB-mediated inflammation

HA Saleh, MH Yousef, A Abdelnaser - Frontiers in immunology, 2021 - frontiersin.org
Innate immune response induces positive inflammatory transducers and regulators in order
to attack pathogens, while simultaneously negative signaling regulators are transcribed to …

Phytochemicals as anti-inflammatory agents in animal models of prevalent inflammatory diseases

SA Shin, BJ Joo, JS Lee, G Ryu, M Han, WY Kim… - Molecules, 2020 - mdpi.com
Phytochemicals are known to have anti-inflammatory effects in vitro and in vivo, such as in
inflammatory disease model systems. Inflammation is an essential immune response to …

Pharmacological effects of polyphenol phytochemicals on the intestinal inflammation via targeting TLR4/NF-κB signaling pathway

C Yu, D Wang, Z Yang, T Wang - International journal of molecular …, 2022 - mdpi.com
TLR4/NF-κB is a key inflammatory signaling transduction pathway, closely involved in cell
differentiation, proliferation, apoptosis, and pro-inflammatory response. Toll like receptor 4 …

Anti‐inflammatory effects of polyphenols in arthritis

F Oliviero, A Scanu, Y Zamudio‐Cuevas… - Journal of the …, 2018 - Wiley Online Library
Polyphenols have been extensively investigated with regard to their antioxidant, anti‐
inflammatory, and immunomodulant properties in many inflammatory chronic conditions …

[HTML][HTML] Managing rheumatoid arthritis with dietary interventions

S Khanna, KS Jaiswal, B Gupta - Frontiers in nutrition, 2017 - frontiersin.org
Self-help by means of dietary interventions can help in management of various disorders
including rheumatoid arthritis (RA), a debilitating autoimmune disease. Dietary interventions …

Anti-inflammatory activity of extra virgin olive oil polyphenols: which role in the prevention and treatment of immune-mediated inflammatory diseases?

C Santangelo, R Vari, B Scazzocchio… - … Metabolic & Immune …, 2018 - ingentaconnect.com
Background and Objective: Altered inflammatory response characterizes chronic
immunemediated inflammatory diseases (IMID) such as rheumatoid arthritis, inflammatory …

A clinical update and global economic burden of rheumatoid arthritis

SA Fazal, M Khan, SE Nishi, F Alam… - … Metabolic & Immune …, 2018 - ingentaconnect.com
Background and Objective: Rheumatoid arthritis (RA) is a predominant inflammatory
autoimmune disorder. The incidence and prevalence of RA is increasing with considerable …

Contribution of Flavonoids and Iridoids to the Hypoglycaemic, Antioxidant, and Nitric Oxide (NO) Inhibitory Activities of Arbutus unedo L.

MC Tenuta, B Deguin, MR Loizzo, A Dugay… - Antioxidants, 2020 - mdpi.com
This study aims at investigating the contribution of two classes of compounds, flavonoids
and iridoids, to the bioactivity of Arbutus unedo L. leaves and fruits. The impact of different …