Challenges to liver transplantation and strategies to improve outcomes

P Dutkowski, M Linecker, ML DeOliveira, B Müllhaupt… - Gastroenterology, 2015 - Elsevier
Liver transplantation (LT) is a highly successful treatment for many patients with
nonmalignant and malignant liver diseases. However, there is a worldwide shortage of …

Liver transplantation for alcoholic hepatitis

GY Im, AM Cameron, MR Lucey - Journal of hepatology, 2019 - Elsevier
While liver transplantation (LT) has become a standard therapy for life-threatening alcohol
related cirrhosis, LT as a treatment for severe alcoholic hepatitis (AH) has remained a taboo …

[PDF][PDF] Diagnosis and treatment of alcohol‐associated liver diseases: 2019 practice guidance from the American Association for the Study of Liver Diseases

DW Crabb, GY Im, G Szabo, JL Mellinger… - Hepatology, 2020 - Wiley Online Library
Alcohol-associated liver disease (ALD) represents a spectrum of liver injury resulting from
alcohol use, ranging from hepatic steatosis to more advanced forms including alcoholic …

ACG clinical guideline: alcoholic liver disease

AK Singal, R Bataller, J Ahn, PS Kamath… - Official journal of the …, 2018 - journals.lww.com
Alcoholic liver disease (ALD) comprises a clinical-histologic spectrum including fatty liver,
alcoholic hepatitis (AH), and cirrhosis with its complications. Most patients are diagnosed at …

Evaluation of early vs standard liver transplant for alcohol-associated liver disease

KM Herrick-Reynolds, G Punchhi, RS Greenberg… - JAMA …, 2021 - jamanetwork.com
Importance Traditionally, liver transplant (LT) for alcohol-associated liver disease (ALD)
requires 6 months of abstinence. Although early LT before 6 months of abstinence has been …

Predicting low risk for sustained alcohol use after early liver transplant for acute alcoholic hepatitis: the sustained alcohol use post–liver transplant score

BP Lee, E Vittinghoff, C Hsu, H Han, G Therapondos… - Hepatology, 2019 - journals.lww.com
Early liver transplant (LT) for alcohol‐associated disease (ie, without a specific sobriety
period) is controversial but increasingly used. Using the multicenter American Consortium of …

[PDF][PDF] Alcohol abstinence in patients surviving an episode of alcoholic hepatitis: prediction and impact on long‐term survival

J Altamirano, H López‐Pelayo, J Michelena… - …, 2017 - Wiley Online Library
Alcoholic hepatitis (AH) is the most severe form of alcoholic liver disease. Most studies have
focused on short‐term prognosis, whereas factors associated with long‐term survival are …

[PDF][PDF] Meeting report: the Dallas consensus conference on liver transplantation for alcohol associated hepatitis

SK Asrani, J Trotter, J Lake, A Ahmed… - Liver …, 2020 - Wiley Online Library
Liver transplantation (LT) for alcohol associated hepatitis (AH) remains controversial. We
convened a consensus conference to examine various aspects of LT for AH. The goal was …

[HTML][HTML] Trajectories of alcohol consumption following liver transplantation

A DiMartini, MA Dew, N Day, MG Fitzgerald… - American Journal of …, 2010 - Elsevier
Any use of alcohol in the years following liver transplantation (LTX) approaches 50% of
patients transplanted for alcoholic liver disease (ALD). We collected detailed prospective …

Indications for liver transplantation

JG O'Leary, R Lepe, GL Davis - Gastroenterology, 2008 - Elsevier
Patients should be considered for liver transplantation if they have evidence of fulminant
hepatic failure, a life-threatening systemic complication of liver disease, or a liver-based …