Technetium‐99m (99mTc) is a widely used radionuclide, and the development of 99mTc
imaging agents continues to be in demand. This overview discusses basic principles of …

The progress in diagnostic nuclear medicine over the years since the discovery of 99mTc is
indeed phenomenal. Over 80% of the radiopharmaceuticals currently being used make use …

This review summarizes some of the developments of metal complexes and metal-complex-
bioconjugates for the diagnosis of disease states that have occurred over the past 10 years …

In a continuing study of Ni11, 111 complexes with lowredox potentialsthat are of possible
relevance to the nickel site in [NiFe]-hydrogenases, Ni" complexes of the tetraanions of the …

The complexes [Tc (CNR) 6] PF6 (where R= zen-butyl, methyl, cyclohexyl, and phenyl) have
been prepared by reduction of the pertechnetate ion with aqueous Na2S204 in thepresence …

Peptides are compounds that contain amino acids (R-aminocarboxylic acids) linked by
amide (peptide) bonds. Designed by nature for stimulating, inhibiting, or regulating …

The detection of human epidermal growth factor receptor type 2 (HER2) expression in
malignant tumors provides important information influencing patient management …

Abstract 99m Tc radiopharmaceuticals play an important role in widespread applications of
nuclear medicine. When 99m Tc radiopharmaceuticals first came into use, major efforts were …

Animal studies have suggested that the nonisomeric N3S triamide mercaptide itgand,
99mTc mercaptoacetyltriglycine (MAG3), may provide a satisfactory"" To-labeled …

Technetium-99m labeling of antibodies has been suboptimal because of low affinity
adventitious binding, nonspecific labeling, and loss of immunoreactivity. The diamide …