With the current pressing need to rise to the ambition of net zero targets to mitigate carbon
emissions and climate change impacts, sustainable processing has never been more …

Today's biologics manufacturing practices incur high costs to the drug makers, which can
contribute to high prices for patients. Timely investment in the development and …

The changing landscape of the biopharmaceutical market is driving a paradigm shift toward
continuous manufacturing. To date, integrated continuous bioprocessing has not been …

Purpose There is a growing interest in continuous biopharmaceutical processing due to the
advantages of small footprint, increased productivity, consistent product quality, high …

In this study, we demonstrated the first, to our knowledge, integrated continuous bioprocess
(ICB) designed for the production of acid‐sensitive monoclonal antibodies, prone to …

Process intensification has shown great potential to increase productivity and reduce costs
in biomanufacturing. This case study describes the evolution of a manufacturing process …

There has been increasing momentum recently in the biopharmaceutical industry to
transition from traditional batch processes to next‐generation integrated and continuous …

An optimization study of an integrated periodic counter-current chromatography (PCC)
process in a monoclonal antibody (mAb) downstream process at lab scale, is presented in …

Viral inactivation plays a critical role in assuring the safety of monoclonal antibody (mAb)
therapeutics. Traditional viral inactivation involves large holding tanks in which product is …

Continuous virus inactivation (VI) has received little attention in the efforts to realize fully
continuous biomanufacturing in the future. Implementation of continuous VI must assure a …