Correlation of UGT1A1* 28 and* 6 polymorphisms with irinotecan-induced neutropenia in Thai colorectal cancer patients
C Atasilp, P Chansriwong, E Sirachainan… - Drug metabolism and …, 2016 - Elsevier
Abstract UDP-glucuronosyltransferase1A1 (UGT1A1) polymorphisms have been related
with irinotecan toxicity. The purpose of this study was to determine the associations between …
with irinotecan toxicity. The purpose of this study was to determine the associations between …
Examination of multiple UGT1A and DPYD polymorphisms has limited ability to predict the toxicity and efficacy of metastatic colorectal cancer treated with irinotecan …
D Liu, J Li, J Gao, Y Li, R Yang, L Shen - BMC cancer, 2017 - Springer
Background To evaluate a new UGT1A and DPYD polymorphism panel to better predict
irinotecan-induced toxicity and the clinical response in Chinese patients with metastatic …
irinotecan-induced toxicity and the clinical response in Chinese patients with metastatic …
Effects of common genetic variants of human uridine diphosphate glucuronosyltransferase subfamilies on irinotecan glucuronidation
K Tagawa, Y Maruo, Y Mimura… - … mechanisms and methods, 2023 - Taylor & Francis
The adverse effects (diarrhea and neutropenia) of irinotecan (7-ethyl-10-[4-(1-piperidino)-1-
piperidino] carbonyloxycamptothecin) are associated with genetic variants of uridine …
piperidino] carbonyloxycamptothecin) are associated with genetic variants of uridine …
Chemoresistance in Colorectal Malignancies: Molecular Mechanisms and Strategies to Overcome.
Colorectal cancer (CRC) remains the third most common cause of cancer-related deaths in
both men and women worldwide. Despite recent advances in clinical practice and effective …
both men and women worldwide. Despite recent advances in clinical practice and effective …
Precision medicine for colorectal cancer
C Hizel, Ş Tüzmen, A Amirfallah… - … in Cancers and …, 2018 - api.taylorfrancis.com
With the changing demographics of the world population and increasing life expectancy,
prostate cancer has become the most common nonskin cancer in developed countries. The …
prostate cancer has become the most common nonskin cancer in developed countries. The …
Novel pharmacogenomic markers of irinotecan-induced severe toxicity in metastatic colorectal cancer patients
SS Chen - 2015 - library-archives.canada.ca
Irinotecan is a cytotoxic agent widely used for the treatment of solid tumors, most particularly
for metastatic colorectal cancers (mCRC). Treatment with this drug frequently results in …
for metastatic colorectal cancers (mCRC). Treatment with this drug frequently results in …
Wechselwirkungen zwischen bioaktiven Sekundärmetaboliten und Irinotecan
D Kronabel - Deutsche Zeitschrift für Onkologie, 2020 - thieme-connect.com
Irinotecan wird seit mehr als zwei Jahrzehnten in unterschiedlichen Arzneiformen, auch in
Kombination mit anderen Arzneistoffen, zur Behandlung einiger Tumorerkrankungen …
Kombination mit anderen Arzneistoffen, zur Behandlung einiger Tumorerkrankungen …