Nonalcoholic fatty liver disease (NAFLD), recently renamed metabolic-associated fatty liver
disease (MAFLD), is one of the most common causes of liver diseases worldwide. NAFLD is …

Perturbations in metabolic pathways can cause substantial increases in plasma and tissue
concentrations of long-chain acylcarnitines (LCACs). For example, the levels of LCACs and …

Non-alcoholic fatty liver is the most common liver disease worldwide. Here, we show that the
mitochondrial protein mitofusin 2 (Mfn2) protects against liver disease. Reduced Mfn2 …

Overcoming resistance to chemotherapies remains a major unmet need for cancers, such as
triple-negative breast cancer (TNBC). Therefore, mechanistic studies to provide insight for …

Endoplasmic reticulum (ER)-mitochondria contacts are critical for the regulation of lipid
transport, synthesis, and metabolism. However, the molecular mechanism and physiological …

Traumatic brain injury (TBI) is a major cause of death and disability in the United States and
causes mitochondrial damage leading to impaired brain function. The purpose of this review …

Hepatic steatosis, the first step in the progression of nonalcoholic fatty liver disease, is
characterized by triglyceride accumulation in hepatocytes and is highly prevalent in people …

Objective The aim of this study was to assess the roles and importance of
phosphatidylserine (PS), an endogenous phospholipid and dietary nutrient, in human brain …

Implementing dissipative assembly in living systems is meaningful for creation of living
materials or even artificial life. However, intracellular dissipative assembly remains scarce …

Suppressive regulatory T cell (Treg) differentiation is controlled by diverse immunometabolic
signaling pathways and intracellular metabolites. Here we show that cell-permeable α …