The trypanosomatids Trypanosoma brucei, Trypanosoma cruzi, and Leishmania spp. are
flagellate eukaryotic parasites that cause serious diseases in humans and animals. These …

Iron is the fourth most abundant element on Earth and the most abundant metal in the
human body. This element is crucial for life because almost all organisms need iron for …

The Trypanosoma brucei flagellum is an essential organelle anchored along the surface of
the cell body through a specialized structure called the flagellum attachment zone (FAZ) …

The hemoflagellate Trypanosoma cruzi is the causative agent of American trypanosomiasis.
Despite the importance of motility in the parasite life cycle, little is known about T. cruzi …

The parasite Trypanosoma cruzi causes Chagas' disease; both heme and ionic Fe are
required for its optimal growth, differentiation, and invasion. Fe is an essential cofactor in …

Trypanosoma cruzi is a parasitic protozoan that infects various species of domestic and wild
animals, triatomine bugs and humans. It is the etiological agent of American …

To carry out the intracellular phase of its life cycle, Trypanosoma cruzi must infect a host cell.
Although a few molecules have been reported to participate in this process, one known …

Chagas disease is caused by the parasitic protozoan Trypanosoma cruzi, which is
transmitted to humans mostly by contact with insects called 'kissing bugs'. The presence of …

2 MATERIALS AND METHODS Trypanosoma cruzi, the etiological agent of Chagas'
disease, has a complex life cycle, alternating between an intermediate invertebrate host and …

Iron is the fourth most abundant element on Earth and is essential for almost all living
organisms. However, it is not accessible to cells in every environment. Ferric iron solubility is …