Since the emergence of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and
Middle East Respiratory Syndrom Coronavirus (MERS-CoV) it has become increasingly …

HIV infection is responsible for one the most devastating human pandemics. The advent of
antiretroviral therapy has changed the course of the pandemic and saved millions of lives …

Context: Lipodystrophies are heterogeneous, genetic or acquired disorders characterized by
selective loss of body fat and predisposition to insulin resistance. The extent of fat loss …

Lipodystrophies, heterogeneous acquired or inherited disorders characterized by the
selective loss of adipose tissue, predispose affected patients to insulin resistance and its …

Antiretroviral toxicity is an increasingly important issue in the management of HIV-infected
patients. With the sustained major declines in opportunistic complications, HIV infection is a …

LONG-TERM REMISSION OF HIV-1 DISEASE CAN BE READILY ACHIEVED by
combinations of antiretroviral agents. The suppression of plasma viral loads to less than the …

Twenty-five years ago, nucleoside analog 3′-azidothymidine (AZT) was shown to efficiently
block the replication of HIV in cell culture. Subsequent studies demonstrated that AZT acts …

Background The use of either efavirenz or lopinavir–ritonavir plus two nucleoside reverse-
transcriptase inhibitors (NRTIs) is recommended for initial therapy for patients with human …

The use of chemotherapy to suppress replication of the human immunodeficiency virus (HIV)
has transformed the face of AIDS in the developed world. Pronounced reductions in illness …

Background Lipodystrophy (peripheral lipoatrophy, central fat accumulation, and
lipomatosis) is a common and disfiguring problem in adult patients with HIV-1 infection on …