Iron metabolism in pathogenic bacteria

C Ratledge, LG Dover - Annual reviews in microbiology, 2000 - annualreviews.org
▪ Abstract The ability of pathogens to obtain iron from transferrins, ferritin, hemoglobin, and
other iron-containing proteins of their host is central to whether they live or die. To combat …

Ecological and molecular investigations of cyanotoxin production

M Kaebernick, BA Neilan - FEMS microbiology ecology, 2001 - academic.oup.com
Cyanobacteria, broadly classi¢ ed as oxygenic phototrophs containing chlorophyll-a and
accessory pigments, are among the oldest life forms on earth. They may be unicellular …

ideR, an Essential Gene in Mycobacterium tuberculosis: Role of IdeR in Iron-Dependent Gene Expression, Iron Metabolism, and Oxidative Stress Response

GM Rodriguez, MI Voskuil, B Gold… - Infection and …, 2002 - Am Soc Microbiol
The mycobacterial IdeR protein is a metal-dependent regulator of the DtxR (diphtheria toxin
repressor) family. In the presence of iron, it binds to a specific DNA sequence in the …

Role of the extracytoplasmic‐function σ Factor σH in Mycobacterium tuberculosis global gene expression

R Manganelli, MI Voskuil, GK Schoolnik… - Molecular …, 2002 - Wiley Online Library
Like other bacterial species, Mycobacterium tuberculosis has multiple sigma (σ) factors
encoded in its genome. In previously published work, we and others have shown that …

Global Analysis of the Mycobacterium tuberculosis Zur (FurB) Regulon

A Maciag, E Dainese, GM Rodriguez… - Journal of …, 2007 - Am Soc Microbiol
The proteins belonging to the Fur family are global regulators of gene expression involved in
the response to several environmental stresses and to the maintenance of divalent cation …

The Mycobacterium tuberculosis IdeR is a dual functional regulator that controls transcription of genes involved in iron acquisition, iron storage and survival in …

B Gold, GM Rodriguez, SAE Marras… - Molecular …, 2001 - Wiley Online Library
In this work, we characterize genes in Mycobacterium tuberculosis that are regulated by
IdeR (i ron‐de pendent r egulator), an iron‐responsive DNA‐binding protein of the DtxR …

Manganese homeostasis in Bacillus subtilis is regulated by MntR, a bifunctional regulator related to the diphtheria toxin repressor family of proteins

Q Que, JD Helmann - Molecular microbiology, 2000 - Wiley Online Library
The Bacillus subtilis yqhN gene encodes a metalloregulatory protein distantly related to the
Corynebacterium diphtheriae diphtheria toxin repressor (DtxR). While DtxR mediates the …

Antigen presentation by CD1: lipids, T cells, and NKT cells in microbial immunity

NR Cohen, S Garg, MB Brenner - Advances in immunology, 2009 - Elsevier
The discovery of molecules capable of presenting lipid antigens, the CD1 family, and of the
T cells that recognize them, has opened a new dimensionin our understanding of cell …

T cell activation by lipopeptide antigens

DB Moody, DC Young, TY Cheng, JP Rosat… - Science, 2004 - science.org
Unlike major histocompatibility proteins, which bind peptides, CD1 proteins display lipid
antigens to T cells. Here, we report that CD1a presents a family of previously unknown …

Sensitive detection of gene expression in mycobacteria under replicating and non-replicating conditions using optimized far-red reporters

P Carroll, LJ Schreuder, J Muwanguzi-Karugaba… - PloS one, 2010 - journals.plos.org
Fluorescent reporter proteins have proven useful for imaging techniques in many organisms.
We constructed optimized expression systems for several fluorescent proteins from the far …