Cells release membrane enclosed nano-sized vesicles termed extracellular vesicles (EVs)
that function as mediators of intercellular communication by transferring biological …

The participation of extracellular vesicles in many cellular processes, including reproduction,
is unquestionable. Although currently, the tetraspanin proteins found in extracellular vesicles …

Extracellular vesicles (EVs) are submicron cell-secreted structures containing proteins,
nucleic acids and lipids. EVs can functionally transfer these cargoes from one cell to another …

Significance: Regulation of cell adhesions during tissue repair is fundamentally important for
cell migration, proliferation, and protein production. All cells interact with extracellular matrix …

Epithelial-mesenchymal transition (EMT) is a highly conserved morphogenic process
defined by the loss of epithelial characteristics and the acquisition of a mesenchymal …

Tissue Inhibitor of Metalloproteases 1, also known as TIMP-1, is named for its well-
established function of inhibiting the proteolytic activity of matrix metalloproteases. Given this …

Mast cells are powerful immune modulators of the tissue microenvironment. Within seconds
of activation, these cells release a variety of preformed biologically active products, followed …

Tetraspanins (Tspans) are a family of four-span transmembrane proteins, known as plasma
membrane “master organizers.” They form Tspan-enriched microdomains (TEMs or TERMs) …

Migrasomes, released by migrating cells, belong to the heterogeneous world of extracellular
vesicles (EVs). However, they can be distinguished from all other members of EVs by their …

Efficient transduction tools are a hallmark for both research and therapy development. Here,
we introduce new insights into the generation of lentiviral vectors with improved …